IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTH CARE WORKERS, AMOL, 2013

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AMINIAN FATEMEH; NIKKHAHAN BABAK; NAZARI ROQAYEH

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Journal: Journal of Mazandaran University of Medical Sciences Year:2014 | Volume:24 | Issue:114 Page(s): 158-162

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Title

IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTH CARE WORKERS, AMOL, 2013

Author(s)

AMINIAN FATEMEH | NIKKHAHAN BABAK | NAZARI ROQAYEH | Issue Writer Certificate

Keywords

HEPATITIS BQ3

IMMUNITYQ3

ANTIBODYQ3

VACCINATIONQ3

Abstract

Background and purpose: VACCINATION against HEPATITIS B is one of the most important ways to prevent this viral disease. However, some individuals vaccinated against HEPATITIS B do not show adequate defense. This study was designed to investigate the immune response towards this disease by assessing the level of HEPATITIS B ANTIBODY in vaccinated health care workers (HCWs) in north of Iran.Material and Methods: This descriptive– cross sectional study was carried out in 2013 in which 117 HCWs of Amol 17 Shahrivar Hospital were studied. Levels of HEPATITIS B surface ANTIBODY were measured in serum samples using ELISA kit. The results were analyzed considering elapsed time of VACCINATION, and age and gender of the subjects.Results: Among the studied HCWs 79 (67.5%) had complete VACCINATION while 38 (32.5%) had incomplete VACCINATION. Immune response was found in safe level in 98 (83.3%) and non-safe in19 (16.2%) (titer below 10mlu/ml). There was a significant correlation between HEPATITIS B surface ANTIBODY levels and elapsed time of VACCINATION (p<0.05). The ANTIBODY titers was higher in women and individuals younger than 40 years of age, however, this difference was not significant (p>0.05).Conclusion: Findings suggest that VACCINATION against HEPATITIS B does not guarantee a complete IMMUNITY and the level of IMMUNITY is very much affected by elapsed time of VACCINATION. Although women were found with higher ANTIBODY titers in this study.

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APA: Copy

AMINIAN, FATEMEH, NIKKHAHAN, BABAK, & NAZARI, ROQAYEH. (2014). IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTH CARE WORKERS, AMOL, 2013. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 24(114), 158-162. SID. https://sid.ir/paper/45746/en

Vancouver: Copy

AMINIAN FATEMEH, NIKKHAHAN BABAK, NAZARI ROQAYEH. IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTH CARE WORKERS, AMOL, 2013. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;24(114):158-162. Available from: https://sid.ir/paper/45746/en

IEEE: Copy

FATEMEH AMINIAN, BABAK NIKKHAHAN, and ROQAYEH NAZARI, “IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTH CARE WORKERS, AMOL, 2013,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 114, pp. 158–162, 2014, [Online]. Available: https://sid.ir/paper/45746/en

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