مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

1,589
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

AN OUTLOOK ON THE ROLE OF GENETIC AND ENVIRONMENTAL FACTORS IN ASTHMA

Pages

  198-212

Abstract

 Background and purpose: ASTHMA is a chronic inflammatory disease of the airways that is caused by hypersensitivity to environmental allergens. Symptoms of ASTHMA include shortness of breath, airway hyper-responsiveness, wheezing, and cough. The disease might vary from a mild to severe and intermittent to chronic disease. ASTHMA is known as a multifactorial disease due to the interaction of genetic and ENVIRONMENTAL FACTORS in its development. Identifying the environmental and GENETIC FACTORS are of great benefit for prevention, diagnosis and treatment of allergic ASTHMA. The aim of this review was to investigate the factors that increase the risk of ASTHMA.Materials and methods: Electronic databases including Scopus, PubMed, Google Scholar, Scientific Information Database (SID), Magiran, and Irandoc were searched for relevant articles published between 1990 and 2016. The search keywords were ASTHMA, ATOPY, GENETIC FACTORS, polymorphisms, ENVIRONMENTAL FACTORS, and gene-environment interaction.Results: This review showed that ASTHMA is a complex and multifactorial disease and the combination and interaction of environmental and GENETIC FACTORS have a role in its development and progression. Therefore, each of these factors cannot be considered as an absolute cause of ASTHMA, but a set of factors such as genes influencing inflammatory pathways, airway rebuilding, and ENVIRONMENTAL FACTORS should be considered as risk factors.Conclusion: ASTHMA is a complex and multifactorial disease and interaction of several genetic and ENVIRONMENTAL FACTORS are involved in its clinical presentation. A major step in determining the genetic causes of ASTHMA is identifying chromosomal regions and candidate genes associated with ASTHMA.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    ALIDADI, RAHIM, ALEKASIR, AZIM, & BIJANZADEH, MAHDI. (2017). AN OUTLOOK ON THE ROLE OF GENETIC AND ENVIRONMENTAL FACTORS IN ASTHMA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 27(151), 198-212. SID. https://sid.ir/paper/46058/en

    Vancouver: Copy

    ALIDADI RAHIM, ALEKASIR AZIM, BIJANZADEH MAHDI. AN OUTLOOK ON THE ROLE OF GENETIC AND ENVIRONMENTAL FACTORS IN ASTHMA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;27(151):198-212. Available from: https://sid.ir/paper/46058/en

    IEEE: Copy

    RAHIM ALIDADI, AZIM ALEKASIR, and MAHDI BIJANZADEH, “AN OUTLOOK ON THE ROLE OF GENETIC AND ENVIRONMENTAL FACTORS IN ASTHMA,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 151, pp. 198–212, 2017, [Online]. Available: https://sid.ir/paper/46058/en

    Related Journal Papers

    Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top