EVALUATION OF KIDNEY FUNCTION IN MALE NEW ZEALAND WHITE RABBITS, SUBSEQUENT TO A 90 DAYS EXPOSURE TO URANYL NITRATE IN THE DRINKING WATER

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MAHMOUDZADEH AZIZ; JAVADI EBRAHIM; MOHSENI Z.; FOROUGHIZADEH MOHSEN

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Journal: Journal of Mazandaran University of Medical Sciences Year:2007 | Volume:17 | Issue:60 Page(s): 108-111

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Title

EVALUATION OF KIDNEY FUNCTION IN MALE NEW ZEALAND WHITE RABBITS, SUBSEQUENT TO A 90 DAYS EXPOSURE TO URANYL NITRATE IN THE DRINKING WATER

Author(s)

MAHMOUDZADEH AZIZ | JAVADI EBRAHIM | MOHSENI Z. | FOROUGHIZADEH MOHSEN | Issue Writer Certificate

Keywords

URANYL NITRATEQ3

NEW ZEALAND RABBITQ3

LABORATORY PARAMETERSQ3

NEPHROTOXICITYQ2

Abstract

Background and purpose: This study was undertaken to examine the reversibility of renal injury in the male New Zealand white rabbits, subsequent to a 90-days exposure to URANYL NITRATE (UN) in the drinking water. Animals were exposed for 90 days to URANYL NITRATE in their drinking water (24 or 500mg/l). The control group was given municipal tap water.Materials and Methods: The biomarkers of kidney function measured in this study includedb-2 micro globulin (marker of tubular), micro albumin (marker of glomerular) and the marker for cell toxicity was catalase.Results: Excretion of b-2 micro globulin was to be significantly different and was correlated with uranium intake for rabbits in early weeks. Microalbuminuria was found to be significantly different but this different was within normal range. Catalasuria was not significantly different in this study.Conclusion: These results suggest that chronic ingestion of uranium in the drinking water affects kidney function and is related to the proximal tubule, rather than glomerul.

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APA: Copy

MAHMOUDZADEH, AZIZ, JAVADI, EBRAHIM, MOHSENI, Z., & FOROUGHIZADEH, MOHSEN. (2007). EVALUATION OF KIDNEY FUNCTION IN MALE NEW ZEALAND WHITE RABBITS, SUBSEQUENT TO A 90 DAYS EXPOSURE TO URANYL NITRATE IN THE DRINKING WATER. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 17(60), 108-111. SID. https://sid.ir/paper/46164/en

Vancouver: Copy

MAHMOUDZADEH AZIZ, JAVADI EBRAHIM, MOHSENI Z., FOROUGHIZADEH MOHSEN. EVALUATION OF KIDNEY FUNCTION IN MALE NEW ZEALAND WHITE RABBITS, SUBSEQUENT TO A 90 DAYS EXPOSURE TO URANYL NITRATE IN THE DRINKING WATER. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;17(60):108-111. Available from: https://sid.ir/paper/46164/en

IEEE: Copy

AZIZ MAHMOUDZADEH, EBRAHIM JAVADI, Z. MOHSENI, and MOHSEN FOROUGHIZADEH, “EVALUATION OF KIDNEY FUNCTION IN MALE NEW ZEALAND WHITE RABBITS, SUBSEQUENT TO A 90 DAYS EXPOSURE TO URANYL NITRATE IN THE DRINKING WATER,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 60, pp. 108–111, 2007, [Online]. Available: https://sid.ir/paper/46164/en

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