ESBLS DISTRIBUTION IN UPEP ISOLATES OF ESCHERICHIA COLI

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MOAZZAMI GOUDARZI MEHDI; HOSSEINI FARZANEH

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2013 | Volume:35 | Issue:4 Page(s): 80-87

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Title

ESBLS DISTRIBUTION IN UPEP ISOLATES OF ESCHERICHIA COLI

Author(s)

MOAZZAMI GOUDARZI MEHDI | HOSSEINI FARZANEH | Issue Writer Certificate

Keywords

ESCHERICHIA COLIQ2

ESBLQ2

ANTIBIOTIC RESISTANCEQ2

Abstract

Backgrounds and Objectives: Despite the widespread availability of antibiotics, ANTIBIOTIC RESISTANCE uropathogens are increasing. The most common mechanism of ANTIBIOTIC RESISTANCE is production of extended spectrum B-lactamas (ESBL). ESBLs are derived from TEM-1 ,TEM-2 and SHV-1 ancestoral plasmids. Currently, according to a variety of mutations in these plasmids, there are more than 90 types for TEM and 25 types for SHV plasmids.Materials and Methods: In this study, 146 uropathogenic ESCHERICHIA COLI (UPEC) isolates were collected. Isolated organisms were identified by standard biochemical and microbial tests. Antibiotic susceptibility was examined by disc diffusion method and isolates with ESBL, were recognized. The presence of TEM and SHV plasmids in isolates were examined by PCR method.Results: According to molecular estimations, TEM and SHV plasmids would be detected in 68.1% of isolates. But, TEM and SHV plasmids were detected in 18.1% and 13.6% of isolates, Separately. It seems that a chromosomal gene of beta lactam resistance was responsible in 52.1% of samples.Conclusion: According to increase level of ANTIBIOTIC RESISTANCE among UEPC isolates, complete recognition of ESBLs is necessary and also trying to understand who they affect antibiotics resistance.

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APA: Copy

MOAZZAMI GOUDARZI, MEHDI, & HOSSEINI, FARZANEH. (2013). ESBLS DISTRIBUTION IN UPEP ISOLATES OF ESCHERICHIA COLI. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 35(4), 80-87. SID. https://sid.ir/paper/46749/en

Vancouver: Copy

MOAZZAMI GOUDARZI MEHDI, HOSSEINI FARZANEH. ESBLS DISTRIBUTION IN UPEP ISOLATES OF ESCHERICHIA COLI. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2013;35(4):80-87. Available from: https://sid.ir/paper/46749/en

IEEE: Copy

MEHDI MOAZZAMI GOUDARZI, and FARZANEH HOSSEINI, “ESBLS DISTRIBUTION IN UPEP ISOLATES OF ESCHERICHIA COLI,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 35, no. 4, pp. 80–87, 2013, [Online]. Available: https://sid.ir/paper/46749/en

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