FEVER AND NEUTROPENIA IN HAEMATO & ONCOLOGIC PATIENTS

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HOSSEINPOUR FEYZI A.A.

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Journal Paper

Paper Information

Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2000 | Volume:34 | Issue:45 Page(s): 29-36

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Information Journal Paper

Title

FEVER AND NEUTROPENIA IN HAEMATO & ONCOLOGIC PATIENTS

Author(s)

HOSSEINPOUR FEYZI A.A. | Issue Writer Certificate

Keywords

FEVERQ3

NEUTROGENAQ2

CEFTIZOXIMEQ3

AMIKACINQ3

Abstract

We have evaluated 45 episodes of FEVER and severe NEUTROGENA, with ANC (Absolute Neutrophil Count) of 92/mm3 and range of 500/mm3-10/mm3 in 38 children with immunocompromising underling diseases, generally post chemotherapy, in a period of 18 months. Their underlying diseases were mainly ALL (Acude Lymphoblastic Leukemia) 62.5% and AML (Acute Myeloblastic Leukaemia) 13.5%. Blood cultures were positive in 24% of episodes, and cultures of localized infectious sites in 7%. The infection was diagnosed clinically and/or radiographically in 37%, but there was no apparent cause for FEVER in 32%. Gram negative enteric microorganisms were isolated in 61.5% and gram positives in 38.5% of positive cultures, E.coli 22.5%, Staph. epidermidis 16.5%, Staph. aureus 16.5%, Pseudomonas aeruginosa 11% , Klebsiella pneumonia 11% , Providencia spp 11%, polygroup Salmonella 5.5%, and P hemolytic Strep. 5.5%. Herpes Zoster virus and Candida were main non bacterial pathogenes. The main localized infections were: pneumonias 23%, gingivostomatitis 23%, I.V. line infection 11.5%, perianal abscess 7.5%, septic arthrtis 4%, G.I. infection 4%, periorbital cellulitis 4%, surgical wound infections 4%, subcutaneous abscess 4%, esophagitis 4% and vulvovaginitis 4%. There was very good response to the first line antibiotics (Amikacine+ CEFTIZOXIME) in 77% of episodes. In 7% of episodes recovery came after adding another antibiotic(s), and in another 7% after complete change of antibiotics. Four patients (9%) died due to polymicrobial sepsis (3) and disseminated H.Z.V infection (1).

Cites

THE PREVALENCE OF BACTEREMIA AMONG HOSPITALIZED CANCER PATIENTS AND ANTIBIOTIC-RESISTANCE OF ISOLATES

References

عفونتهای باکتریایی در بیماران مبتلا به بدخیمی های خونی در مرکز آموزشی انکولوژی هماتولوژی شهید قاضی تبریز

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APA: Copy

HOSSEINPOUR FEYZI, A.A.. (2000). FEVER AND NEUTROPENIA IN HAEMATO & ONCOLOGIC PATIENTS. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 34(45), 29-36. SID. https://sid.ir/paper/46940/en

Vancouver: Copy

HOSSEINPOUR FEYZI A.A.. FEVER AND NEUTROPENIA IN HAEMATO & ONCOLOGIC PATIENTS. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2000;34(45):29-36. Available from: https://sid.ir/paper/46940/en

IEEE: Copy

A.A. HOSSEINPOUR FEYZI, “FEVER AND NEUTROPENIA IN HAEMATO & ONCOLOGIC PATIENTS,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 34, no. 45, pp. 29–36, 2000, [Online]. Available: https://sid.ir/paper/46940/en

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