EFFECTS OF HYPOTHERMIA ON MEMORY CONSOLIDATION IN MALE RATS

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BABRI SH.; KHAMENEH SAEID; MOTAMEDI F.

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2004 | Volume:- | Issue:61 Page(s): 13-16

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Title

EFFECTS OF HYPOTHERMIA ON MEMORY CONSOLIDATION IN MALE RATS

Author(s)

BABRI SH. | KHAMENEH SAEID | MOTAMEDI F. | Issue Writer Certificate

Keywords

MEMORYQ2

HYPOTHERMIAQ2

HALOTHANEQ4

AMNESIAQ2

PASSIVE AVOIDANCEQ4

Abstract

Background and Objectives: The process through which MEMORY is formed and factors affecting it, are among issues under scrutiny in neuroscience. These, however, lack many undiscovered aspects. On the other hand, the wide spectrum of utilization of HYPOTHERMIA for medical and surgical purposes, raises the question of the effect on MEMORY. Materials and Methods: In the present study 70 male wistar rats were randomly divided into 7 groups (A-G, 10 rats each). Control group (group A) was trained using "passive avoidance technique" and then the degree of their consolidation of MEMORY was tested 24hours later. This was incorpororated as basic protocol for other groups. Groups B and C also went under HALOTHANE anaesthesia for 15 and 60 minutes respectively immediately after training. These behaved as second line control groups. For the groups left, groups D and F received 15 minutes HALOTHANE anaesthesia plus HYPOTHERMIA, 28±1 C and 24±1 C respectively. Groups E and G were the same as groups D and F but the length of HYPOTHERMIA was 60 minutes. Results: Results obtained indicated no significant effect of HALOTHANE and superficial HYPOTHERMIA (28±1c) for 15min on MEMORY consolidation, but deep HYPOTHERMIA (24±1C) for 15 and 60 minutes had significant effects (p<0.05) on MEMORY retrieval.Conclusion: Results suggest that mild HYPOTHERMIA in a short time has no effects on MEMORY but deep HYPOTHERMIA at the same time, produces significant effects on MEMORY consolidation.

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APA: Copy

BABRI, SH., KHAMENEH, SAEID, & MOTAMEDI, F.. (2004). EFFECTS OF HYPOTHERMIA ON MEMORY CONSOLIDATION IN MALE RATS . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, -(61), 13-16. SID. https://sid.ir/paper/47021/en

Vancouver: Copy

BABRI SH., KHAMENEH SAEID, MOTAMEDI F.. EFFECTS OF HYPOTHERMIA ON MEMORY CONSOLIDATION IN MALE RATS . MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;-(61):13-16. Available from: https://sid.ir/paper/47021/en

IEEE: Copy

SH. BABRI, SAEID KHAMENEH, and F. MOTAMEDI, “EFFECTS OF HYPOTHERMIA ON MEMORY CONSOLIDATION IN MALE RATS ,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. -, no. 61, pp. 13–16, 2004, [Online]. Available: https://sid.ir/paper/47021/en

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