STUDY OF FOKI AND APAI POLYMORPHISMS OF VITAMIN D RECEPTOR GENE IN IRANIAN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SALEHI SHARAREH; SHARAFI HEIDAR; HAKIM SEYED MOJTABA; RANJBAR OMRANI GHOLAM HOSEIN; EBRAHIMI FATEMEH; POURYASIN ALI

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2016 | Volume:38 | Issue:3 Page(s): 78-83

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

693

Download:

Cites:

Information Journal Paper

Title

STUDY OF FOKI AND APAI POLYMORPHISMS OF VITAMIN D RECEPTOR GENE IN IRANIAN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS

Author(s)

Keywords

CALCIUMQ3

GENETIC POLYMORPHISMQ2

OSTEOPOROSISQ2

VITAMIN D RECEPTORQ2

Abstract

Background & Objectives: OSTEOPOROSIS along with decreased bone density can lead to bone structure loss which increases the risk of fractures. Recent identification of genetic factors impels researchers to assess association of genetic variations with OSTEOPOROSIS. The aim of this study was to evaluate the relationship between FokI and ApaI polymorphisms of VITAMIN D RECEPTOR (VDR) gene and serum CALCIUM level, serum 25-OH vitamin D level and OSTEOPOROSIS in Iranian postmenopausal women.Materials and Methods: In this study, we included 194 over 50 years old postmenopausal women with OSTEOPOROSIS and osteopenia and 50 over 50 years old healthy postmenopausal women as the control group. To study the polymorphisms, genomic DNA was extracted from blood samples containing EDTA anticoagulant. Genotyping of FokI and ApaI polymorphisms of VDR gene was performed using PCR-RFLP method.Results: Weight, height, age, serum 25-OH vitamin D, and CALCIUM level were compared in three groups of control, osteopenia, and OSTEOPOROSIS. The mean of serum CALCIUM level was not significantly different but the means of age, weight, height, and serum 25-OH vitamin D level were significantly different between the patients and control group. Also, the differences in the distribution of FokI and ApaI genotypes were not statistically significant among the patients with osteopenia, OSTEOPOROSIS and the control group.Conclusion: It seems that there is no association between FokI and ApaI polymorphisms of VDR gene and OSTEOPOROSIS.

Cites

No record.

References

No record.

Cite

APA: Copy

SALEHI, SHARAREH, SHARAFI, HEIDAR, HAKIM, SEYED MOJTABA, RANJBAR OMRANI, GHOLAM HOSEIN, EBRAHIMI, FATEMEH, & POURYASIN, ALI. (2016). STUDY OF FOKI AND APAI POLYMORPHISMS OF VITAMIN D RECEPTOR GENE IN IRANIAN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 38(3 ), 78-83. SID. https://sid.ir/paper/47382/en

Vancouver: Copy

SALEHI SHARAREH, SHARAFI HEIDAR, HAKIM SEYED MOJTABA, RANJBAR OMRANI GHOLAM HOSEIN, EBRAHIMI FATEMEH, POURYASIN ALI. STUDY OF FOKI AND APAI POLYMORPHISMS OF VITAMIN D RECEPTOR GENE IN IRANIAN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;38(3 ):78-83. Available from: https://sid.ir/paper/47382/en

IEEE: Copy

SHARAREH SALEHI, HEIDAR SHARAFI, SEYED MOJTABA HAKIM, GHOLAM HOSEIN RANJBAR OMRANI, FATEMEH EBRAHIMI, and ALI POURYASIN, “STUDY OF FOKI AND APAI POLYMORPHISMS OF VITAMIN D RECEPTOR GENE IN IRANIAN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 38, no. 3 , pp. 78–83, 2016, [Online]. Available: https://sid.ir/paper/47382/en

Related Journal Papers