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Title

EVALUATION OF THE EFFECT OF GARLIC POWDER ON BLOOD PRESSURE, SERUM LIPIDS AND LIPOPROTEINS

Pages

  15-20

Abstract

 Recently it has been reported that garlic extract inhibits LDL Oxidation and minimize oxidized LDL-induced cell injury. In this study, the antioxidant effects of garlic were further examined by determining changes in serum levels of lipids and LIPOPROTEINS and also BLOOD PRESSURE in normal individuals following receiving garlic powder.Serum levels of lipids and LIPOPROTEINS (cholesterol, Triglyceride, LDL-c and HDL-c) and BLOOD PRESSURE were measured in thirty one apparently healthy male students between 21-25 years old. An the students were nonsmoker living in university residency with similar nutritional status. the students received garlic powder (3/400 mg/d) (each Dose equivalent to 1000 microgram Allicin) for four weaks. Then measurement of the parameters was repeated and the results were compared with those of obtained at the banging. Cholesterol, Triglyceride and HDL-c were measured by standard enzgmatic methods. Total lipids were determined calorimetrically using phosphoric Acid-Vanllin Reaction and LDL-c Calculated by Friedewald formula and BLOOD PRESSURE was measured with standard method. Using test the results obtained before and after taking garlic powder were compared with each others. Reduction in the serum levels of total cholesterol triglyceride, LDL-c, tolal lipids and elevation in the levels of HDL-c and in the HDL-c/LDL-c ratio were observed but only in the cases of total lipids and HPL-c/LDL-c ratio the changes were significant (P<0.05 in both cases). Comparing the results of BLOOD PRESSUREs although reduction in systolic and diastolic pressures was noticed but it was not significant (P>0.05).Since elevation in the Levels of total Lipids and ratio of HDL-c/LDL-c may promote atherosclerosis garlic may thus be useful for the prevention of atherosclerosis and cardiovascular diseases by reducing formation of oxidized lipids and altering their metabolism.

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    APA: Copy

    TOUHIDI, MOHAMMAD, & RAHBANI, M.. (2001). EVALUATION OF THE EFFECT OF GARLIC POWDER ON BLOOD PRESSURE, SERUM LIPIDS AND LIPOPROTEINS. PHARMACEUTICAL SCIENCES, -(4), 15-20. SID. https://sid.ir/paper/48491/en

    Vancouver: Copy

    TOUHIDI MOHAMMAD, RAHBANI M.. EVALUATION OF THE EFFECT OF GARLIC POWDER ON BLOOD PRESSURE, SERUM LIPIDS AND LIPOPROTEINS. PHARMACEUTICAL SCIENCES[Internet]. 2001;-(4):15-20. Available from: https://sid.ir/paper/48491/en

    IEEE: Copy

    MOHAMMAD TOUHIDI, and M. RAHBANI, “EVALUATION OF THE EFFECT OF GARLIC POWDER ON BLOOD PRESSURE, SERUM LIPIDS AND LIPOPROTEINS,” PHARMACEUTICAL SCIENCES, vol. -, no. 4, pp. 15–20, 2001, [Online]. Available: https://sid.ir/paper/48491/en

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