DEXAMETHASONE EFFICACY ON POSTOPERATIVE NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY IN WOMENS

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SOLYMANI S.; KOLAHDOUZAN KH.

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Journal: PHARMACEUTICAL SCIENCES Year:2002 | Volume:- | Issue:1 Page(s): 47-52

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Information Journal Paper

Title

DEXAMETHASONE EFFICACY ON POSTOPERATIVE NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY IN WOMENS

Author(s)

SOLYMANI S. | KOLAHDOUZAN KH. | Issue Writer Certificate

Keywords

DEXAMETHASONEQ3

METOCLOPRAMIDQ3

LAPAROSCOPYQ3

NAUSEAQ3

VOMITINGQ3

Abstract

Background: Postoperative NAUSEA and VOMITING is among the most unpleasant experiences associated with laparoscopic surgery. To evaluate the prophylactic effect of DEXAMETHASONE (5mg) on postoperative NAUSEA and VOMITING (PONV) in women undergoing laparoscopic surgery. Sixty women (n=20 in each of the three groups) undergoing laparoscopic cholecystectomy under general anesthesia were enrolled in this randomized, double-blinded, placebo-controlled study. After tracheal intubation, group I received IV DEXAMETHASONE 5mg, whereas groups II and III received IV METOCLOPRAMID 10mg and saline, respectively. Patient in group I reported a lower incidence of PONY and requested less rescue antiemetics than those in group III during the first four postoperative hours (P<0.01). patients in group I reported a lower incidence of PONY than those in groups II (P<0.05) and ill (P<0.01) during the 24-hr post operative period. Group II and III did not differ from each other in the incidence of PONY and the proportion of patients who requested rescue anti emetics. Prophylactic IV DEXAMETHASONE (5mg) significantly reduces the incidence of PONV in women undergoing laparoscopic cholecystectomy. At this dose, DEXAMETHASONE is more effective than METOCLOPRAMID 10 mg or saline.

Cites

THE COMPARISON OF DEXAMETHASONE AND METOCLOPRAMIDE EFFECTS ON POSTOPERATIVE NAUSEA AND VOMITING

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APA: Copy

SOLYMANI, S., & KOLAHDOUZAN, KH.. (2002). DEXAMETHASONE EFFICACY ON POSTOPERATIVE NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY IN WOMENS. PHARMACEUTICAL SCIENCES, -(1), 47-52. SID. https://sid.ir/paper/48601/en

Vancouver: Copy

SOLYMANI S., KOLAHDOUZAN KH.. DEXAMETHASONE EFFICACY ON POSTOPERATIVE NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY IN WOMENS. PHARMACEUTICAL SCIENCES[Internet]. 2002;-(1):47-52. Available from: https://sid.ir/paper/48601/en

IEEE: Copy

S. SOLYMANI, and KH. KOLAHDOUZAN, “DEXAMETHASONE EFFICACY ON POSTOPERATIVE NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY IN WOMENS,” PHARMACEUTICAL SCIENCES, vol. -, no. 1, pp. 47–52, 2002, [Online]. Available: https://sid.ir/paper/48601/en

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