STUDIES ON FORMULATION OF SUSTAINED RELEASE SODIUM DICLOFENAC AND RELEASE KINETIC

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DABAGH M.A.; ESHGHI L.

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Journal: PHARMACEUTICAL SCIENCES Year:2003 | Volume:- | Issue:2 Page(s): 17-26

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Information Journal Paper

Title

STUDIES ON FORMULATION OF SUSTAINED RELEASE SODIUM DICLOFENAC AND RELEASE KINETIC

Author(s)

DABAGH M.A. | ESHGHI L. | Issue Writer Certificate

Keywords

RELEASEQ2

KINETICQ3

B-CYCLODEXTRINQ3

SODIUM DICLOFENACQ2

Abstract

The aim of this research is formulation of sustained RELEASE Diclofenac sodium tablet. In this research, diclofenac sodium (The drug), and polymers such as Ethylcellulose (EC), Eudragit, Hydroxypropyl methylcellulose (HPMC), and p-cyclodextrin (P-CD) were used. Tablets were prepared from different ratios of the drug and the polymers by the slug method. The RELEASE profiles from prepared tablets were obtained by the USP XXII (Apparatus II) in phosphate buffer (pH=6.8) at 37±0.5°C and rotation rate of 100 rpm. The best prepared formulation (J), in comparison with the commercial tablet, was chosen by the dissolution testing method. The curve of RELEASE of diclofenac sodium up to 98% RELEASE was linear when plotted as a function of the square root of time.

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APA: Copy

DABAGH, M.A., & ESHGHI, L.. (2003). STUDIES ON FORMULATION OF SUSTAINED RELEASE SODIUM DICLOFENAC AND RELEASE KINETIC. PHARMACEUTICAL SCIENCES, -(2), 17-26. SID. https://sid.ir/paper/48649/en

Vancouver: Copy

DABAGH M.A., ESHGHI L.. STUDIES ON FORMULATION OF SUSTAINED RELEASE SODIUM DICLOFENAC AND RELEASE KINETIC. PHARMACEUTICAL SCIENCES[Internet]. 2003;-(2):17-26. Available from: https://sid.ir/paper/48649/en

IEEE: Copy

M.A. DABAGH, and L. ESHGHI, “STUDIES ON FORMULATION OF SUSTAINED RELEASE SODIUM DICLOFENAC AND RELEASE KINETIC,” PHARMACEUTICAL SCIENCES, vol. -, no. 2, pp. 17–26, 2003, [Online]. Available: https://sid.ir/paper/48649/en

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