A COMPARISON STUDY OF AGNORS STAINING IN HUMAN ORAL NORMAL MUCOSA, VERRUCOUS CARCINOMA, AND SQUAMOUS CELL CARCINOMA

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MOHTASHAM N.; SHARIFI N.; KAMIAB K.

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Journal: IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY Year:2005 | Volume:17 | Issue:2 (40) Page(s): 21-26

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Title

A COMPARISON STUDY OF AGNORS STAINING IN HUMAN ORAL NORMAL MUCOSA, VERRUCOUS CARCINOMA, AND SQUAMOUS CELL CARCINOMA

Author(s)

MOHTASHAM N. | SHARIFI N. | KAMIAB K. | | Issue Writer Certificate

Keywords

AGNORQ3

VERRUCOUS CARCINOMAQ3

SQUAMOUS CELL CARCINOMAQ2

ORAL CAVITYQ3

Abstract

Introduction: The value of Silver Staining of nucleolar organizer regions (AGNOR) counts as a diagnostic aid has been reported for several neoplastic entities. The aim of this was study to determine the evaluation of the expression of AGNOR as a marker of proliferation in SQUAMOUS CELL CARCINOMA grade I, VERRUCOUS CARCINOMA and oral normal mucosa.Methods: Silver-Stain nucleolar organizer regions AGNORs were counted in sections from formalin - fixed paraffin embedded blocks of 20 cases of well differentiated SQUAMOUS CELL CARCINOMA, 20 cases of VERRUCOUS CARCINOMA and 10 cases of normal oral mucosa. Two methods of AGNORs counting were used. The mean number of AGNOR nucleus (M AGNORs) and determination cells containing 3 or more AGNORs/ nucleus (P AGNOR) as indicator of the proliferative activity of the cells. Results: Statistical differences were found between normal oral mucosa, VERRUCOUS CARCINOMA and WD SQUAMOUS CELL CARCINOMA in AGNOR related parameters.Conclusion: AGNOR would be a quantitative, discriminative aid, easy to monitor in a pathology laboratory in detection incipient cellular alterations and contribute to the issue of early diagnosis and to the knowledge of tumoral growth.

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APA: Copy

MOHTASHAM, N., SHARIFI, N., & KAMIAB, K.. (2005). A COMPARISON STUDY OF AGNORS STAINING IN HUMAN ORAL NORMAL MUCOSA, VERRUCOUS CARCINOMA, AND SQUAMOUS CELL CARCINOMA. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, 17(2 (40)), 21-26. SID. https://sid.ir/paper/49453/en

Vancouver: Copy

MOHTASHAM N., SHARIFI N., KAMIAB K.. A COMPARISON STUDY OF AGNORS STAINING IN HUMAN ORAL NORMAL MUCOSA, VERRUCOUS CARCINOMA, AND SQUAMOUS CELL CARCINOMA. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY[Internet]. 2005;17(2 (40)):21-26. Available from: https://sid.ir/paper/49453/en

IEEE: Copy

N. MOHTASHAM, N. SHARIFI, and K. KAMIAB, “A COMPARISON STUDY OF AGNORS STAINING IN HUMAN ORAL NORMAL MUCOSA, VERRUCOUS CARCINOMA, AND SQUAMOUS CELL CARCINOMA,” IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol. 17, no. 2 (40), pp. 21–26, 2005, [Online]. Available: https://sid.ir/paper/49453/en

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