THE EFFECT OF MIDAZOLAM ON THE DURATION ON LIDOCAINE INTERATHECAL BLOCK

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REZVANI MEHRAN; TALAKOOB REIHANAK; HAJALIKHANI AMENE

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:28 | Issue:118 Page(s): 1296-1303

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Title

THE EFFECT OF MIDAZOLAM ON THE DURATION ON LIDOCAINE INTERATHECAL BLOCK

Author(s)

REZVANI MEHRAN | TALAKOOB REIHANAK | HAJALIKHANI AMENE | Issue Writer Certificate

Keywords

MIDAZOLAMQ3

LIDOCAINEQ2

SPINAL ANESTHESIAQ2

Abstract

Background: One of the issues anesthesia specialists permanently are faced with in spinal blocks is the prolongation of the surgery more what had been estimated. Provided that intravenous MIDAZOLAM can increase duration of LIDOCAINE interathecal block, it would solve the problem.Methods: This was a double-blind clinical trial study in which adults underwent elective abdominal surgery and lower extremities of ASA, I, II and studied in two 18-member groups. MIDAZOLAM group (0.03 mg/kg) underwent the intervention as MIDAZOLAM 2mg+fentanyl 1mg/kg (5 min after administration of MIDAZOLAM) and the control group as normal saline 2cc+fentanyl 1mg/kg (5 min after administration of normal saline). The highest level of sensory block, duration of sensory block, duration of motor (movement) block and recovery duration were measured and documented.Finding: Mean duration of sensory block had no significant difference between the two groups; however, duration of motor block for the MIDAZOLAM group was 82.9±27.3 minutes which significantly was more than control group with 59.1±26.5 minutes (P=0.01). The median of sensory block level for MIDAZOLAM and control groups respectively were T8 and T10 and according to nonparametric median test, the median of sensory block level had a significant difference in the two groups (P=0.02). The average duration of stay in the recovery, in the patients of MIDAZOLAM group was 116.1±29.6 minutes and in the control group also was 87.8±24.1 minutes which significantly it was higher in MIDAZOLAM group (P=0.002).Conclusion: The present study indicated that intravenous MIDAZOLAM injection in SPINAL ANESTHESIA with LIDOCAINE increased the duration of motor block without any side effects (nausea, vomiting and respiratory distress), and caused more hemodynamic and saturation loss of arterial blood pressure.

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APA: Copy

REZVANI, MEHRAN, TALAKOOB, REIHANAK, & HAJALIKHANI, AMENE. (2011). THE EFFECT OF MIDAZOLAM ON THE DURATION ON LIDOCAINE INTERATHECAL BLOCK. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 28(118), 1296-1303. SID. https://sid.ir/paper/49659/en

Vancouver: Copy

REZVANI MEHRAN, TALAKOOB REIHANAK, HAJALIKHANI AMENE. THE EFFECT OF MIDAZOLAM ON THE DURATION ON LIDOCAINE INTERATHECAL BLOCK. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;28(118):1296-1303. Available from: https://sid.ir/paper/49659/en

IEEE: Copy

MEHRAN REZVANI, REIHANAK TALAKOOB, and AMENE HAJALIKHANI, “THE EFFECT OF MIDAZOLAM ON THE DURATION ON LIDOCAINE INTERATHECAL BLOCK,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 28, no. 118, pp. 1296–1303, 2011, [Online]. Available: https://sid.ir/paper/49659/en

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