MOLECULAR TYPING OF CANDIDA ALBICANS ISOLATES RECOVERED FROM HUMAN IMMUNODEFICIENCY VIRUS (HIV)-INFECTED PATIENTS WITH OROPHARYNGEAL CANDIDIASIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KATIRAEE FARZAD; KHOSRAVI ALI REZA; KHALAJ VAHID; TARGHIBI JILA; HAJI ABDOLBAGHI MAHBOOBEH

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2014 | Volume:31 | Issue:270 Page(s): 2362-2372

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,065

Download:

Cites:

Information Journal Paper

Title

MOLECULAR TYPING OF CANDIDA ALBICANS ISOLATES RECOVERED FROM HUMAN IMMUNODEFICIENCY VIRUS (HIV)-INFECTED PATIENTS WITH OROPHARYNGEAL CANDIDIASIS

Author(s)

Keywords

OROPHARYNGEAL CANDIDIASISQ2

CANDIDA ALBICANSQ2

GENOTYPINGQ2

HUMAN IMMUNODEFICIENCY VIRUS (HIV)Q2

INFECTED PATIENTSQ2

Abstract

Background: In HUMAN IMMUNODEFICIENCY VIRUS (HIV)-infected patients, OROPHARYNGEAL CANDIDIASIS is a common infection. The aim of present study was molecular typing of CANDIDA ALBICANS isolates recovered from HIV-infected patients with OROPHARYNGEAL CANDIDIASIS and comparing the molecular patterns of fluconazole-resistant and susceptible isolates.Methods: The molecular typing of genomic DNA of 48 CANDIDA ALBICANS isolated from HIV-infected patients were assessed by the random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) fingerprinting. Sensitivity of strains to fluconazole was determined by the broth microdilution method.Findings: We detected two main clusters and seven sub-clusters, comprising 24 genotypes of CANDIDA ALBICANS strains. No associations between the patterns of strains isolated from hospitalized patients and outpatients and clinical forms of OROPHARYNGEAL CANDIDIASIS were detected. There was also a relative correlation between fluconazole susceptibility and strain clustering.Conclusion: The presence of several genotypes of CANDIDA ALBICANS in HIV-infected patients would lead to problems in the treatment and prevention of oral candidiasis. The lack of correlation between genotypes and clinical forms of OROPHARYNGEAL CANDIDIASIS shows the importance pf host condition in the pathogenesis of candida infections. The lack of phylogenetic relationships among strains from hospitalized patients approves endogenous origin of candida infection. The results indicate that HIV-infected patients have favorable conditions for the growth and proliferation of different genotypes of CANDIDA ALBICANS. In conclusion, molecular typing using RAPD-PCR revealed a genomic heterogeneity in the CANDIDA ALBICANS clinical isolates studied in HIV-infected patients.

Cites

EVALUATION OF CONFIRMED CASES OF ORAL CANDIDIASIS ON THE BASIS OF ITS RISK FACTORS IN PATIENTS REFERRING TO THE ORAL MEDICINE DEPARTMENT OF YAZD FACULTY OF DENTISTRY FROM 2013 TO 2015

References

No record.

Cite

APA: Copy

KATIRAEE, FARZAD, KHOSRAVI, ALI REZA, KHALAJ, VAHID, TARGHIBI, JILA, & HAJI ABDOLBAGHI, MAHBOOBEH. (2014). MOLECULAR TYPING OF CANDIDA ALBICANS ISOLATES RECOVERED FROM HUMAN IMMUNODEFICIENCY VIRUS (HIV)-INFECTED PATIENTS WITH OROPHARYNGEAL CANDIDIASIS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 31(270), 2362-2372. SID. https://sid.ir/paper/49858/en

Vancouver: Copy

KATIRAEE FARZAD, KHOSRAVI ALI REZA, KHALAJ VAHID, TARGHIBI JILA, HAJI ABDOLBAGHI MAHBOOBEH. MOLECULAR TYPING OF CANDIDA ALBICANS ISOLATES RECOVERED FROM HUMAN IMMUNODEFICIENCY VIRUS (HIV)-INFECTED PATIENTS WITH OROPHARYNGEAL CANDIDIASIS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2014;31(270):2362-2372. Available from: https://sid.ir/paper/49858/en

IEEE: Copy

FARZAD KATIRAEE, ALI REZA KHOSRAVI, VAHID KHALAJ, JILA TARGHIBI, and MAHBOOBEH HAJI ABDOLBAGHI, “MOLECULAR TYPING OF CANDIDA ALBICANS ISOLATES RECOVERED FROM HUMAN IMMUNODEFICIENCY VIRUS (HIV)-INFECTED PATIENTS WITH OROPHARYNGEAL CANDIDIASIS,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 31, no. 270, pp. 2362–2372, 2014, [Online]. Available: https://sid.ir/paper/49858/en

Related Journal Papers