THE EFFICACY OF PROPHYLACTIC INTRAVENOUS AMINOPHYLLINE, PARACETAMOL OR AMINOPHYLLINE AND PARACETAMOL IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP

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JABALAMELI MITRA; SADAT SEYED MASOUD

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Journal Paper

Paper Information

Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2016 | Volume:34 | Issue:400 Page(s): 1144-1150

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Title

THE EFFICACY OF PROPHYLACTIC INTRAVENOUS AMINOPHYLLINE, PARACETAMOL OR AMINOPHYLLINE AND PARACETAMOL IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP

Author(s)

JABALAMELI MITRA | SADAT SEYED MASOUD | Issue Writer Certificate

Keywords

POSTQ2

DURALQ2

PUNCTURE HEADACHEQ2

PREVENTIONQ2

AMINOPHYLLINEQ2

PARACETAMOLQ2

Abstract

Background: POST-dural-puncture headache (PDPH) is commonly seen after neuroaxial block and several types of regimens have been suggested for treatment. This study aimed to evaluate the effects of AMINOPHYLLINE, PARACETAMOL and administration of AMINOPHYLLINE and PARACETAMOL concurrently on PREVENTION of POST-dural-puncture headache.Methods: In a double-blind randomized clinical trial, we evaluated 136 patients in four groups (n = 34) undergoing spinal anesthesia for elective cesarean section in Shahid Beheshti and Alzahra hospitals of Isfahan province, Iran, during March to December 2015. After umbilical cord clamping, in four group AMINOPHYLLINE (1.5 mg/kg), PARACETAMOL (12.5 mg/kg), AMINOPHYLLINE and PARACETAMOL with the same dose and normal saline was injected slowly intravenously. Before spinal anesthesia, each 15 minutes during execute time of surgery and in recovery room, every 6 hours in first day and daily in first weak after the surgery, incidence of POST-dural-puncture headache in each group was evaluated.Findings: 42 patients (33.88%) out of the 136 ones suffered from headache. 26.5% of patients who had received AMINOPHYLLINE 32.4%, of patients who had received PARACETAMOL 14.7%, of patients who had received AMINOPHYLLINE and PARACETAMOL and 50% of patients who had not received any drug suffered from headache (P=0.007).Conclusion: This study shows that intravenous administration of AMINOPHYLLINE and PARACETAMOL significantly reduces the incidence of POST-dural-puncture headache in cesarean section and we can use this regimen for PREVENTION.

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References

EFFECT OF VENOUS DEXAMETHASONE, ORAL CAFFEINE AND ACETAMINOPHEN ON RELATIVE FREQUENCY AND INTENSITY OF POSTDURAL PUNCTURE HEADACHE AFTER SPINAL ANESTHESIA

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APA: Copy

JABALAMELI, MITRA, & SADAT, SEYED MASOUD. (2016). THE EFFICACY OF PROPHYLACTIC INTRAVENOUS AMINOPHYLLINE, PARACETAMOL OR AMINOPHYLLINE AND PARACETAMOL IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 34(400), 1144-1150. SID. https://sid.ir/paper/50162/en

Vancouver: Copy

JABALAMELI MITRA, SADAT SEYED MASOUD. THE EFFICACY OF PROPHYLACTIC INTRAVENOUS AMINOPHYLLINE, PARACETAMOL OR AMINOPHYLLINE AND PARACETAMOL IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2016;34(400):1144-1150. Available from: https://sid.ir/paper/50162/en

IEEE: Copy

MITRA JABALAMELI, and SEYED MASOUD SADAT, “THE EFFICACY OF PROPHYLACTIC INTRAVENOUS AMINOPHYLLINE, PARACETAMOL OR AMINOPHYLLINE AND PARACETAMOL IN PREVENTION OF HEADACHE STRIKES DUE TO SPINAL ANESTHESIA IN CESAREAN SECTIONS COMPARED TO THE CONTROL GROUP,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 34, no. 400, pp. 1144–1150, 2016, [Online]. Available: https://sid.ir/paper/50162/en

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