VITAMIN D RECEPTOR (VDR) GENE BSMI POLYMORPHISMS IN LUPUS NEPHRITIS

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ABBASI MAHNAZ; REZAIEYAZDI ZAHRA; TAVAKOL AFSHARI JALIL; HATEF MOHAMMADREZA; SAHEBARI MARYAM

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:28 | Issue:119 Page(s): 1311-1316

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Title

VITAMIN D RECEPTOR (VDR) GENE BSMI POLYMORPHISMS IN LUPUS NEPHRITIS

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Keywords

VITAMIN D RECEPTOR GENEQ3

BSMIQ3

LUPUS NEPHRITISQ3

Abstract

Background: Vitamin D has immunomodulatory function. Polymorphisms of the gene encoding the vitamin D receptor detected by BSMI may be source of diversity in its action. An association between VITAMIN D RECEPTOR GENE BSMI polymorphisms and LUPUS NEPHRITIS has been reported. This study was performed to evaluate VITAMIN D RECEPTOR GENE BSMI polymorphisms in LUPUS NEPHRITIS.Methods: Twenty nine patients with LUPUS NEPHRITIS enrolled in this study. VITAMIN D RECEPTOR GENE typing was performed based on polymerase chain reaction-restriction fragment length polymorphism.Finding: Vitamin D receptor genotyping of BSMI polymorphisms was 20.6% for BB, 51.7% for Bb, and 27.5% for bb without statistically significant difference (P=0.090). In 21 patients that renal biopsy was done, the Bb genotype was the most (42.8%). There was not any correlation between renal histology and VITAMIN D RECEPTOR GENE BSMI polymorphisms (P=0.068).Conclusion: There was no relationship between VITAMIN D RECEPTOR GENE BSMI polymorphisms and LUPUS NEPHRITIS.

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APA: Copy

ABBASI, MAHNAZ, REZAIEYAZDI, ZAHRA, TAVAKOL AFSHARI, JALIL, HATEF, MOHAMMADREZA, & SAHEBARI, MARYAM. (2011). VITAMIN D RECEPTOR (VDR) GENE BSMI POLYMORPHISMS IN LUPUS NEPHRITIS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 28(119), 1311-1316. SID. https://sid.ir/paper/50378/en

Vancouver: Copy

ABBASI MAHNAZ, REZAIEYAZDI ZAHRA, TAVAKOL AFSHARI JALIL, HATEF MOHAMMADREZA, SAHEBARI MARYAM. VITAMIN D RECEPTOR (VDR) GENE BSMI POLYMORPHISMS IN LUPUS NEPHRITIS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;28(119):1311-1316. Available from: https://sid.ir/paper/50378/en

IEEE: Copy

MAHNAZ ABBASI, ZAHRA REZAIEYAZDI, JALIL TAVAKOL AFSHARI, MOHAMMADREZA HATEF, and MARYAM SAHEBARI, “VITAMIN D RECEPTOR (VDR) GENE BSMI POLYMORPHISMS IN LUPUS NEPHRITIS,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 28, no. 119, pp. 1311–1316, 2011, [Online]. Available: https://sid.ir/paper/50378/en

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