A STUDY OF THE EFFECT OF FRANKINCENSE EXTRACT ON THE WALL OF CORONARY ARTERIES (ANTERIOR AND POSTERIOR INTER-VENTRICULAR BRANCHES) IN HIGH-CHOLESTEROL FED MALE RABBITS

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DASHTI GH.R.; ESFANDIARI E.; NEMATBAKHSH M.; SANEEI M.H.; JAAFARI BARMAK M.

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Paper Information

Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2005 | Volume:23 | Issue:79 Page(s): 63-68

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Title

A STUDY OF THE EFFECT OF FRANKINCENSE EXTRACT ON THE WALL OF CORONARY ARTERIES (ANTERIOR AND POSTERIOR INTER-VENTRICULAR BRANCHES) IN HIGH-CHOLESTEROL FED MALE RABBITS

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Keywords

FRANKINCENSEQ4

CHOLESTEROLQ3

ANTERIOR INTER-VENTRICULAR ARTERYQ3

FATTY STREAKQ3

Abstract

Introduction: Atherosclerosis and coronary artery diseases are the most prevalent causes of mortality and morbidity in developing countries. The useful effect of FRANKINCENSE extract on various organs has been reported. The purpose of this study was to determine the effect of FRANKINCENSE extract on the wall of anterior and posterior inter-ventricular branches of coronary arteries in male rabbits fed with high CHOLESTEROL diet.Methods: Twenty white male rabbits were weighed (wt=1.780 kg) and randomly divided into two groups. For 40 days, group I (n=10) was given high-cholesterol (1%) diet with FRANKINCENSE extract (500mg/kg) and group 2 (n=10) was fed with high-cholesterol diet along with distilled water. They were weighed and then the animals were sacrificed. The anterior and posterior inter-ventricular branches of coronary arteries were dissected and pathological sections were stained with H & E and studied by light microscope.Results: The weight of the rabbits before and after the experiment in both the groups showed significant difference (P<0.05). Rabbits that received FRANKINCENSE extract also showed significant difference in mean pathological scoring of anterior and posterior inter-ventricular branches of coronary arteries (P<0.05). Group 1 exhibited a significant decrease in the formation of FATTY STREAKs compared group 2.Discussion: Pathological assessment showed that the rabbits which had received FRANKINCENSE extract did not develop accumulation of FATTY STREAKs in anterior and posterior inter-ventricular branches of coronary arteries, whereas those which had received a high-cholesterol diet had FATTY STREAKs. It was shown that FRANKINCENSE extract can significantly inhibit the formation of FATTY STREAKs, thus preventing cardiovascular diseases and atherosclerosis and lowering serum lipids.

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APA: Copy

DASHTI, GH.R., ESFANDIARI, E., NEMATBAKHSH, M., SANEEI, M.H., & JAAFARI BARMAK, M.. (2005). A STUDY OF THE EFFECT OF FRANKINCENSE EXTRACT ON THE WALL OF CORONARY ARTERIES (ANTERIOR AND POSTERIOR INTER-VENTRICULAR BRANCHES) IN HIGH-CHOLESTEROL FED MALE RABBITS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 23(79), 63-68. SID. https://sid.ir/paper/50923/en

Vancouver: Copy

DASHTI GH.R., ESFANDIARI E., NEMATBAKHSH M., SANEEI M.H., JAAFARI BARMAK M.. A STUDY OF THE EFFECT OF FRANKINCENSE EXTRACT ON THE WALL OF CORONARY ARTERIES (ANTERIOR AND POSTERIOR INTER-VENTRICULAR BRANCHES) IN HIGH-CHOLESTEROL FED MALE RABBITS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2005;23(79):63-68. Available from: https://sid.ir/paper/50923/en

IEEE: Copy

GH.R. DASHTI, E. ESFANDIARI, M. NEMATBAKHSH, M.H. SANEEI, and M. JAAFARI BARMAK, “A STUDY OF THE EFFECT OF FRANKINCENSE EXTRACT ON THE WALL OF CORONARY ARTERIES (ANTERIOR AND POSTERIOR INTER-VENTRICULAR BRANCHES) IN HIGH-CHOLESTEROL FED MALE RABBITS,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 23, no. 79, pp. 63–68, 2005, [Online]. Available: https://sid.ir/paper/50923/en

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