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Information Journal Paper

Title

BRUCELLA: PATHOGENESIS, IMMUNE SYSTEM RESPONSE AND VACCINE

Pages

  1-19

Abstract

 Bacteria of the genus BRUCELLA are intracellular pathogens capable of surviving and replicating within MACROPHAGEs of mammalian hosts. Resistance to killing in professional phagocytic cells controls survival and chronic infection. Recent advances have shed light on virulence factors and host functions involved at various stages of the BRUCELLA intracellular life cycle. This review focuses on how this pathogen uses multiple strategies to circumvent MACROPHAGE defense mechanisms and generate an organelle permissive for replication. In addition, we discuss about host immune responses to BRUCELLA and new strategies are used to produce an efficient VACCINE against BRUCELLA infection.

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  • Cite

    APA: Copy

    GHASEMI, AMIR, & RANJBAR, REZA. (2014). BRUCELLA: PATHOGENESIS, IMMUNE SYSTEM RESPONSE AND VACCINE. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 32(295), 1-19. SID. https://sid.ir/paper/50951/en

    Vancouver: Copy

    GHASEMI AMIR, RANJBAR REZA. BRUCELLA: PATHOGENESIS, IMMUNE SYSTEM RESPONSE AND VACCINE. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2014;32(295):1-19. Available from: https://sid.ir/paper/50951/en

    IEEE: Copy

    AMIR GHASEMI, and REZA RANJBAR, “BRUCELLA: PATHOGENESIS, IMMUNE SYSTEM RESPONSE AND VACCINE,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 32, no. 295, pp. 1–19, 2014, [Online]. Available: https://sid.ir/paper/50951/en

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