PERIODONTAL DISEASE AS A RISK FACTOR FOR CARDIOVASCULAR DISEASE

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HASHEMIAN S.H.; BANIHASHEMI S.A.

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Title

PERIODONTAL DISEASE AS A RISK FACTOR FOR CARDIOVASCULAR DISEASE

Author(s)

HASHEMIAN S.H. | BANIHASHEMI S.A. | Issue Writer Certificate

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Abstract

Now evidence is mounting that suggests people with periodontal disease a bacterial infection, may be more at risk for heart disease and have nearly twice the risk of having a fatal heart attack, than patients without periodontal disease. It is our central hypothesis that periodontal disease, which are chronic Gram-negative infections, represent a previously unrecognized risk factor for atherosclerosis and thromboembolic events. Previous studies have demonstrated an association between periodontal disease severity and risk of coronary heart disease-and stroke. We hypothesize that this association may be due to an underlying inflammatory response trait, which places an individual at high risk for developing both periodontal disease and atherosclerosis. We further suggest that periodontal disease, once established, provides a biological burden of endotocxin (Lipoplysaccharide) and inflammatory cytokines (especially TXA2, IL-1, PGE2, and TNF-a) which serve to initiate and exacerbate atherogenesis and thromboembolic events. While more research is needed to confirm how periodontal bacteria may affect your heart, one possibility is that periodontal bacteria enter the blood through inflamed gums and cause small blood clots that contribute to clogged arteries.Another possibility is that the inflammation caused by periodontal disease contributes to the buildup of fatty deposits inside heart arteries.

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APA: Copy

HASHEMIAN, S.H., & BANIHASHEMI, S.A.. (2000). PERIODONTAL DISEASE AS A RISK FACTOR FOR CARDIOVASCULAR DISEASE. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 43(67), 83-88. SID. https://sid.ir/paper/51402/en

Vancouver: Copy

HASHEMIAN S.H., BANIHASHEMI S.A.. PERIODONTAL DISEASE AS A RISK FACTOR FOR CARDIOVASCULAR DISEASE. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2000;43(67):83-88. Available from: https://sid.ir/paper/51402/en

IEEE: Copy

S.H. HASHEMIAN, and S.A. BANIHASHEMI, “PERIODONTAL DISEASE AS A RISK FACTOR FOR CARDIOVASCULAR DISEASE,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 43, no. 67, pp. 83–88, 2000, [Online]. Available: https://sid.ir/paper/51402/en

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