ASSOCIATION OF HTLV-I WITH AUTOIMMUNE THYROIDITIS IN PATIENTS WITH MYELOPATHY/TROPICAL SPASTIC PARAPARESIS AND IN HTLV-I CARRIERS

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TAGHAVI MORTEZA; FARID HOSSEINI REZA; AYAT ELAHI HOSSEIN

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2010 | Volume:53 | Issue:1 Page(s): 7-10

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Title

ASSOCIATION OF HTLV-I WITH AUTOIMMUNE THYROIDITIS IN PATIENTS WITH MYELOPATHY/TROPICAL SPASTIC PARAPARESIS AND IN HTLV-I CARRIERS

Author(s)

TAGHAVI MORTEZA | FARID HOSSEINI REZA | AYAT ELAHI HOSSEIN | Issue Writer Certificate

Keywords

HAM/TSPQ3

HASHIMOTO’S THYROIDITISQ3

HTLVIQ3

Abstract

Introduction: There are some reports about the association of autoimmune thyroid diseases with human T cell leukemia virus type I (HTLV-I) infection. The objective of this study was to estimate the seroprevalence rates of anti-thyroid antibodies in HTLV-I carriers and HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients in Mashhad, north east of Iran, to determine any association between HTLV-I infection and HASHIMOTO’S THYROIDITIS (HT).Materials and Methods: A total of 46 HTLV-I infected patients (24 patients with HAM/TSP and 22 asymptomatic carriers) and 40 HTLV-I seronegative healthy individuals were screened for the presence of thyroid autoantibodies. The diagnosis of HT was based on the presence of positive thyroid autoantibodies (Anti thyroid peroxidase and/or Anti thyroglobulin) and at least one of two additional criteria (hypothyroidism and/or goiter). Analysis of data was done, using Fisher-Exact test by statistical software SPSS version 13.0. A P value below 0.05 was considered statistically significant. Results: Positivity for thyroid autoantibodies was found in 14 (63.6%) of 22 asymptomatic carriers, 6 (25%) of 24 patients with HAM/TSP and 3 (7.5%) of 40 HTLV-I seronegative healthy individuals. HT found in 45.4% of asymptomatic carriers, 25% of HAM/TSP patients and 5% of seronegative healthy individuals.Conclusion: This study demonstrates a high prevalence of HT in the HAM/TSP patients and the HTLV-I carriers in Mashhad. Our findings suggest an association between HTLV-I infection and HT in our region.

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APA: Copy

TAGHAVI, MORTEZA, FARID HOSSEINI, REZA, & AYAT ELAHI, HOSSEIN. (2010). ASSOCIATION OF HTLV-I WITH AUTOIMMUNE THYROIDITIS IN PATIENTS WITH MYELOPATHY/TROPICAL SPASTIC PARAPARESIS AND IN HTLV-I CARRIERS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 53(1), 7-10. SID. https://sid.ir/paper/51554/en

Vancouver: Copy

TAGHAVI MORTEZA, FARID HOSSEINI REZA, AYAT ELAHI HOSSEIN. ASSOCIATION OF HTLV-I WITH AUTOIMMUNE THYROIDITIS IN PATIENTS WITH MYELOPATHY/TROPICAL SPASTIC PARAPARESIS AND IN HTLV-I CARRIERS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;53(1):7-10. Available from: https://sid.ir/paper/51554/en

IEEE: Copy

MORTEZA TAGHAVI, REZA FARID HOSSEINI, and HOSSEIN AYAT ELAHI, “ASSOCIATION OF HTLV-I WITH AUTOIMMUNE THYROIDITIS IN PATIENTS WITH MYELOPATHY/TROPICAL SPASTIC PARAPARESIS AND IN HTLV-I CARRIERS,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 53, no. 1, pp. 7–10, 2010, [Online]. Available: https://sid.ir/paper/51554/en

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