Determining Related Factors to Survival of Colorectal Cancer Patients Using Cox Regression

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Sabouri Samaneh; ESMAILY HABIBOLLAH; SHAHID SALES SOUDABEH; Emadi Mehdi

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2018 | Volume:61 | Issue:4 Page(s): 1082-1092

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Title

Determining Related Factors to Survival of Colorectal Cancer Patients Using Cox Regression

Author(s)

Sabouri Samaneh | ESMAILY HABIBOLLAH | SHAHID SALES SOUDABEH | Emadi Mehdi | Issue Writer Certificate

Keywords

Colorectal Cancer (CRC)Q2

Survival AnalysisQ2

Cox RegressionQ2

Abstract

Introduction Colorectal cancer (CRC) is the third common cancer worldwide and its death rate is increasing in Iran. The present study was conducted with the purpose of determining related factors to CRC patients’ survival using Cox Regression model. Methods In a historical cohort, we examined 404 subjects who were diagnosed with CRC and referred to Omid Hospital in Mashhad from 2006 through 2011. First demographic and clinical information of patients were gathered and then followed until September 2016. In this study, Cox Regression was utilized to investigate related factors to CRC patients’ survival. For statistical analysis SPSS software was applied and significant level was 0. 05. Results In this research, 217 men (53. 7%) and 187 women (46. 3%) were studied. The mean± sd of subjects’ age was 56. 4± 14. 7 years and 3-year, 5-year and 7-year survival rates of patients were 0. 60, 0. 50 and 0. 48 respectively. In this study, the median (95% confidence interval) of survival times was calculated 5. 48 (3. 07, 7. 90). According to Cox Regression model, BMI (p=0. 024), first treatment (p=0. 019), stage (p<0. 0001) and relapse (p=0. 002) were related to patients’ survival. Conclusion Numerous studies are conducted for Survival Analysis of CRC patients that they differ in results in some cases. Doing more researches, applying other statistical analysis methods is suggested; therefore, with identifying related factors to patients’ survival we can contribute suitable medical resources to high risk patients.

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APA: Copy

Sabouri, Samaneh, ESMAILY, HABIBOLLAH, SHAHID SALES, SOUDABEH, & Emadi, Mehdi. (2018). Determining Related Factors to Survival of Colorectal Cancer Patients Using Cox Regression. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 61(4 ), 1082-1092. SID. https://sid.ir/paper/51997/en

Vancouver: Copy

Sabouri Samaneh, ESMAILY HABIBOLLAH, SHAHID SALES SOUDABEH, Emadi Mehdi. Determining Related Factors to Survival of Colorectal Cancer Patients Using Cox Regression. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;61(4 ):1082-1092. Available from: https://sid.ir/paper/51997/en

IEEE: Copy

Samaneh Sabouri, HABIBOLLAH ESMAILY, SOUDABEH SHAHID SALES, and Mehdi Emadi, “Determining Related Factors to Survival of Colorectal Cancer Patients Using Cox Regression,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 61, no. 4 , pp. 1082–1092, 2018, [Online]. Available: https://sid.ir/paper/51997/en

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