ENDOCRINE DISORDER IN CHILDREN WITH CHRONIC LIVER DISEASES

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KIANIFAR HAMIDREZA; PARTOVI SIMIN; JAFARI SEYED ALI; ALIZADEH NAZANIN; KHAKSHOUR ALI; KHORASHADI ZADEH FATEMEH

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2012 | Volume:55 | Issue:1 Page(s): 15-20

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Title

ENDOCRINE DISORDER IN CHILDREN WITH CHRONIC LIVER DISEASES

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Keywords

CHILDRENQ2

CHRONIC LIVER DISEASEQ3

ENDOCRINEQ3

Abstract

Introduction: An important consequence of CHRONIC LIVER DISEASE (CLD) is ENDOCRINE disorders. The main object of this study was to assess serum hormones in CHILDREN with CLD.Materials and Methods: In a cross sectional study between 2007-2009 ,57 CHILDREN with CHRONIC LIVER DISEASE were enrolled. Levels of serum triiodothyronine (T3), thyroxin (T4) , thyroid stimulating hormone (TSH), parathormon (PTH), calcium (c), phosphor (P) ,alkalanephosphatase (ALP),growth hormone (GH) and insulin like growth factor-1 (IGF-1), albumin (ALB) and total protein, triglyceride (TG) and cholesterol (CHOL), fasting blood sugar (FBS) and liver function tests were measured.Results: In this study, most patients' thyroid hormones and fasting blood sugar were at normal range. But there was a significant decline in serum IGF-1 levels in this patients. 28 percent of CHILDREN had PTH levels higher than normal range for age and 24 percent had serum phosphor levels lower than normal range. 1.3 of these patients were bone fracture. Overt diabetics did not obsereve in our CHILDREN.Conclusion: CHILDREN with CLD are GH resistant and might be at risk of osteopenia and bone fracture. So serum hormone levels should be carefully monitored in CHILDREN with CLD.

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APA: Copy

KIANIFAR, HAMIDREZA, PARTOVI, SIMIN, JAFARI, SEYED ALI, ALIZADEH, NAZANIN, KHAKSHOUR, ALI, & KHORASHADI ZADEH, FATEMEH. (2012). ENDOCRINE DISORDER IN CHILDREN WITH CHRONIC LIVER DISEASES. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 55(1), 15-20. SID. https://sid.ir/paper/52173/en

Vancouver: Copy

KIANIFAR HAMIDREZA, PARTOVI SIMIN, JAFARI SEYED ALI, ALIZADEH NAZANIN, KHAKSHOUR ALI, KHORASHADI ZADEH FATEMEH. ENDOCRINE DISORDER IN CHILDREN WITH CHRONIC LIVER DISEASES. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;55(1):15-20. Available from: https://sid.ir/paper/52173/en

IEEE: Copy

HAMIDREZA KIANIFAR, SIMIN PARTOVI, SEYED ALI JAFARI, NAZANIN ALIZADEH, ALI KHAKSHOUR, and FATEMEH KHORASHADI ZADEH, “ENDOCRINE DISORDER IN CHILDREN WITH CHRONIC LIVER DISEASES,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 55, no. 1, pp. 15–20, 2012, [Online]. Available: https://sid.ir/paper/52173/en

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