THE EFFECT OF BOTULINUM TOXIN SPASTICITY IN CHILDREN WITH CEREBRAL PALSY

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ASHRAFZADEH F.; FARAJI M.; TABARESTANI S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Medical Journal of Mashhad University of Medical Sciences Year:2003 | Volume:46 | Issue:80 Page(s): 47-52

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Title

THE EFFECT OF BOTULINUM TOXIN SPASTICITY IN CHILDREN WITH CEREBRAL PALSY

Author(s)

ASHRAFZADEH F. | FARAJI M. | TABARESTANI S. | Issue Writer Certificate

Keywords

CEREBRAL PALSYQ2

CHILDRENQ3

BOTULINUM TOXINQ4

Abstract

The use of BOTULINUM TOXIN type A (BTA) was studied in 15 CHILDREN with spastic diplegia to determine its efficacy and tolerability. Nine non-ambulatory and six nonfunctional ambulatory were included. All CHILDREN received occupational therapy for 6 months. They did not show any clinical improvement, then BTA were injected. The effect was evident within one week. The peak effect was noticed by one month in the majority. The effect lasted for 3-6 months.All CHILDREN experienced decreased spasticitiy scores. The peak improvement in active dorsiflexion was noticed in the third month. Their functional status improved, six nonambulatory CHILDREN becoming more independently ambulatory. Measurement of joint showed improvement in the range of motion as compared with the baseline.Side effects consist of pain at the site of injection and temporary weakness in the four CHILDREN. This study demonstrated that BOTULINUM TOXIN type A (BTA) is useful in reducing the spasticity in CEREBRAL PALSY.

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APA: Copy

ASHRAFZADEH, F., FARAJI, M., & TABARESTANI, S.. (2003). THE EFFECT OF BOTULINUM TOXIN SPASTICITY IN CHILDREN WITH CEREBRAL PALSY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 46(80), 47-52. SID. https://sid.ir/paper/52296/en

Vancouver: Copy

ASHRAFZADEH F., FARAJI M., TABARESTANI S.. THE EFFECT OF BOTULINUM TOXIN SPASTICITY IN CHILDREN WITH CEREBRAL PALSY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2003;46(80):47-52. Available from: https://sid.ir/paper/52296/en

IEEE: Copy

F. ASHRAFZADEH, M. FARAJI, and S. TABARESTANI, “THE EFFECT OF BOTULINUM TOXIN SPASTICITY IN CHILDREN WITH CEREBRAL PALSY,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 46, no. 80, pp. 47–52, 2003, [Online]. Available: https://sid.ir/paper/52296/en

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