MUSCLE RELAXANT AND HYPNOTIC EFFECTS OF SALVIA LERIIFOLIA BENTH LEAVES EXTRACT IN MICE

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HOSSEINZADEH H.; HASSAN ZADEH A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian Journal of Basic Medical Sciences Year:2001 | Volume:4 | Issue:3 (11) Page(s): 130-138

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Title

MUSCLE RELAXANT AND HYPNOTIC EFFECTS OF SALVIA LERIIFOLIA BENTH LEAVES EXTRACT IN MICE

Author(s)

HOSSEINZADEH H. | HASSAN ZADEH A. | Issue Writer Certificate

Keywords

SALVIA LERIIFOLIA; MUSCLE RELAXANTQ4

HYPNOTICQ2

TRACTION TESTQ2

HERBAL MEDICINEQ4

Abstract

Muscle relaxant and HYPNOTIC effects of Salvia leriifolia Benth. aqueous decoction leaves extract was studied in mice. The aqueous decoction extract (1.15 and 1.57 g/kg, i.p.) slightly increased sleeping time up to 20.58 min versus 63.67 min in diazepam (3 mg/kg) group in thiopental-hypnosis test. The extract (0.29-2.87 mg/kg, i.p.) induced relaxation of skeletal muscle in mice verified by TRACTION TEST. The extract at low dose (0.29 mg/kg) showed a muscle relaxant activity as effective as diazepam (1 mg/kg). Preliminary phytochemical test showed that the extract contains low flavonoid, rich tannin and saponin. Our observation confirmed that S. leriifolia aqueous leaves extract exerted muscle relaxant and HYPNOTIC effects.

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References

اثرات عصاره های آبی و الکلی دانه و برگ گیاه نوروزک (Salvia leriifolia) بر مدت زمان زنده ماندن موش های در معرض هیپوکسی

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APA: Copy

HOSSEINZADEH, H., & HASSAN ZADEH, A.. (2001). MUSCLE RELAXANT AND HYPNOTIC EFFECTS OF SALVIA LERIIFOLIA BENTH LEAVES EXTRACT IN MICE. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 4(3 (11)), 130-138. SID. https://sid.ir/paper/52463/en

Vancouver: Copy

HOSSEINZADEH H., HASSAN ZADEH A.. MUSCLE RELAXANT AND HYPNOTIC EFFECTS OF SALVIA LERIIFOLIA BENTH LEAVES EXTRACT IN MICE. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2001;4(3 (11)):130-138. Available from: https://sid.ir/paper/52463/en

IEEE: Copy

H. HOSSEINZADEH, and A. HASSAN ZADEH, “MUSCLE RELAXANT AND HYPNOTIC EFFECTS OF SALVIA LERIIFOLIA BENTH LEAVES EXTRACT IN MICE,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 4, no. 3 (11), pp. 130–138, 2001, [Online]. Available: https://sid.ir/paper/52463/en

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