MORPHOLOGICAL CHANGES OCCURING IN THE DEVELOPING MICE CHOROID PLEXUS

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NIKRAVESH M.R.; JALALI M.

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Journal: Iranian Journal of Basic Medical Sciences Year:2002 | Volume:5 | Issue:1 (13) Page(s): 44-51

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Title

MORPHOLOGICAL CHANGES OCCURING IN THE DEVELOPING MICE CHOROID PLEXUS

Author(s)

NIKRAVESH M.R. | JALALI M. | Issue Writer Certificate

Keywords

CHOROID PLEXUSQ4

DEVELOPMENTQ2

MICEQ2

Abstract

Introduction: The morphogenesis of the paraventricular CHOROID PLEXUS (PCP) was studied during different life periods in MICE (balb/c) by histochemical methods. Methods: Fetal and postnatal brain MICE, fixed in formalin 10%, provided coronal and horizontal serial sections and stained for light microscopic study. Results and Discussion: Based on this investigation, PCP in MICE appears on post conception day (PCD) 11 with the formation of a horizontal crest in the roof of the interventricular foramen and apical portion of the fourth ventricle. During these changes the epithelial cells differentiate and stratify to form the choroid plaque. From PCD 11 the developing CHOROID PLEXUS (CP) expands into the ventricular cavity taking with it mesenchyme and vessels. Light microsopic studies show that differential epithelial cells are more cylindrical and their nuclei become more elongated. These cells in microscopic view exhibit prolongations into the ventricular cavities. Apical ends of the epithelial cells show numerous elevations into the choroid lakes. During these morphogenical changes other cells appear in neighboring areas of these formations, named epiplexus cells. Morphological studies in old MICE show atrophy and flattening of the CP epithelial cell layer. Other morphological changes in old CP was irregularity of the epithelial basement membrane but previous changes do not show in fetal and early postnatal groups.

Cites

STUDY OF BASEMENT MEMBRANE TYPE IV COLLAGEN APPEARANCE IN THE BRAIN CHOROIDS PLEXUS OF MOUSE FETUSES

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APA: Copy

NIKRAVESH, M.R., & JALALI, M.. (2002). MORPHOLOGICAL CHANGES OCCURING IN THE DEVELOPING MICE CHOROID PLEXUS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 5(1 (13)), 44-51. SID. https://sid.ir/paper/52511/en

Vancouver: Copy

NIKRAVESH M.R., JALALI M.. MORPHOLOGICAL CHANGES OCCURING IN THE DEVELOPING MICE CHOROID PLEXUS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2002;5(1 (13)):44-51. Available from: https://sid.ir/paper/52511/en

IEEE: Copy

M.R. NIKRAVESH, and M. JALALI, “MORPHOLOGICAL CHANGES OCCURING IN THE DEVELOPING MICE CHOROID PLEXUS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 5, no. 1 (13), pp. 44–51, 2002, [Online]. Available: https://sid.ir/paper/52511/en

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