MORE APPROPRIATE ANTIMICROBIAL AGENTS FOR ANTIBIOGRAM

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MASOMI J.; YADEGARI D.; MOZONI SH.

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2005 | Volume:10 | Issue:29 Page(s): 53-58

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Title

MORE APPROPRIATE ANTIMICROBIAL AGENTS FOR ANTIBIOGRAM

Author(s)

MASOMI J. | YADEGARI D. | MOZONI SH. | Issue Writer Certificate

Keywords

ANTIBIOGRAMQ3

SUSCEPTIBILITY TESTINGQ3

IRANQ3

Abstract

Background: Antibiotics used for antimicrobial SUSCEPTIBILITY TESTING is usually rewised yearly by the National Committee for Clinical Laboratory Standards (NCCLS).Emergence of drug resistance among local bacterial strains, and unsatisfaction of clinicians to the antimicrobial susceptibility test results are the main problems in the treatment of Infectious diseases. The purpose of this study was to select the more appropriate antimicrobial agents for ANTIBIOGRAM and also to satisfy practitioners and help them in choosing the best drug treatments.Methods: The study was carried out in shohada-e-Tajrish teaching hospital, Tehran, in 2004. A preliminary information about antimicrobial agents was obtained from the NCCLS guidelines and other standard references. Clinical experiences and recommendations of the hospital faculty members, experts from Infectious diseases research centers and also pharmacists in Tehran were collected. On the basis of the collected data, a new list of antimicrobial agents was prepared. Results: Antimicrobial agents recommended by the Hospital Practitioners are summarized. Then according to the NCCLS guidelines and recommendations of the clinicians, various antimicrobial agents were selected which are listed in four tables based on types of samples and bacterial isolates. Each of the tables consist of part "A" and part "B", in which part "A" is for primary and part "B" for secondary ANTIBIOGRAM. The hospital clinicians such as Professors of the Urology department of the hospital suggested that: 1) Ciprotloxacin and Nortloxacin may be used for primary ANTIBIOGRAM of the gram negative isolates, but Azithromycin and Nortloxacin for secondary ANTIBIOGRAM ; 2) Ceftazidime for the grame negative isolates from urinary and other tluid samples ; 3) Ceftriaxone may be included in primary ANTIBIOGRAMs of gram negative organisms isolated from different fluid samples. Surgeons and Internists recommended Cefazolin and Coamoxyclav, respectively. However the clinicians did not recommend the use of chloramphenicol. Tazocin (Pipracillin + Tazobactam) was recommended by the Nephrologists for secondary ANTIBIOGRAM of gram negative isolates of upper urinary tract infections.Conclusions: Antimicrobial agents used for SUSCEPTIBILITY TESTING were rewised by using international references and local clinical data which may help clinicians in choosing appropriate drug therapy for local resistant strains of different Infectious agents. It is recommended that this model of study may be carried out in different medical institutions and resultant proposed panels of drugs rewised yearly and then used as IRANian NCCLS guidelines.

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APA: Copy

MASOMI, J., YADEGARI, D., & MOZONI, SH.. (2005). MORE APPROPRIATE ANTIMICROBIAL AGENTS FOR ANTIBIOGRAM. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 10(29), 53-58. SID. https://sid.ir/paper/52749/en

Vancouver: Copy

MASOMI J., YADEGARI D., MOZONI SH.. MORE APPROPRIATE ANTIMICROBIAL AGENTS FOR ANTIBIOGRAM. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2005;10(29):53-58. Available from: https://sid.ir/paper/52749/en

IEEE: Copy

J. MASOMI, D. YADEGARI, and SH. MOZONI, “MORE APPROPRIATE ANTIMICROBIAL AGENTS FOR ANTIBIOGRAM,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 10, no. 29, pp. 53–58, 2005, [Online]. Available: https://sid.ir/paper/52749/en

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