TT VIRUS INFECTION IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN

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GACHKAR L.; KHERADPEZHOUH M.; TAREMI M.; KHOUSHBATEN M.; AGHABOZORGY S.; NAGILI B.

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2005 | Volume:10 | Issue:29 Page(s): 13-20

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Title

TT VIRUS INFECTION IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN

Author(s)

Keywords

TTVQ4

HEMODIALYSISQ4

TABRIZQ3

IRANQ3

Abstract

Background: The TT virus (TTV) is a recently discovered DNA virus, which was first identified in patients with non A to G hepatitis following blood transfusion. Transmission is generally via the parenteral route but recent data suggest that TTV can also be transmitted by the fecal-oral route.Methods: This cross-sectional study was conducted in March 2005. 324 Patients on maintenance HEMODIALYSIS at three different centers in the city of TABRIZ were invited to participate. Demographic and clinical data were registered. Blood samples for virological and routine biochemical tests were drawn simultaneously. TTV DNA was detected using seminested polymerase chain reaction (PCR). All patients were previously tested for HBs Ag, anti- HCV and anti-HIV by EIA assay.Results: The overall seroprevalence of TTV was 9.3% ( 95% Cl: 6.1%-12.5%). The prevalence rate of HBV, HCV and HEV infection were 4.6% (95% Cl: 2.3%-6.9%) and 20.4% (95% Cl:16%-24.8%) and 7.4 % ( 95% Cl: 4.6%-10.6%), respectively. No relations were found between TTV infection and elevated levels of alanine aminotransferase (ALT). No significant association was found between anti-HEV positivity and age, sex, duration of HEMODIALYSIS, positivity for hepatitis B or C virus infection markers and history of transfusion.Conclusion: We observed low TTV prevalence; there was no association between TTV and blood borne infections (HBV, HCV, and HIV) in our HD patients. This is the first report concerning seroepidemiology of TTV infection in a large group of chronic HD individuals in IRAN.

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APA: Copy

GACHKAR, L., KHERADPEZHOUH, M., TAREMI, M., KHOUSHBATEN, M., AGHABOZORGY, S., & NAGILI, B.. (2005). TT VIRUS INFECTION IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 10(29), 13-20. SID. https://sid.ir/paper/52755/en

Vancouver: Copy

GACHKAR L., KHERADPEZHOUH M., TAREMI M., KHOUSHBATEN M., AGHABOZORGY S., NAGILI B.. TT VIRUS INFECTION IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2005;10(29):13-20. Available from: https://sid.ir/paper/52755/en

IEEE: Copy

L. GACHKAR, M. KHERADPEZHOUH, M. TAREMI, M. KHOUSHBATEN, S. AGHABOZORGY, and B. NAGILI, “TT VIRUS INFECTION IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 10, no. 29, pp. 13–20, 2005, [Online]. Available: https://sid.ir/paper/52755/en

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