STRONGYLOIDIASIS HYPERINFECTION SYNDROME IN KHOUZESTAN PROVINCE, SOUTHWEST IRAN AND MOLECULAR CHARACTERIZATION OF ISOLATES RECOVERED FROM THE PATIENTS

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NILFOROUSHAN M.R.; KIA E.B.; MIRHENDI H.; REZAEI SASAN; MOUBEDI I.; MARAGHI S.

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2007 | Volume:12 | Issue:36 Page(s): 45-48

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Title

STRONGYLOIDIASIS HYPERINFECTION SYNDROME IN KHOUZESTAN PROVINCE, SOUTHWEST IRAN AND MOLECULAR CHARACTERIZATION OF ISOLATES RECOVERED FROM THE PATIENTS

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Keywords

STRONGYLOIDIASISQ3

HYPERINFECTIONQ3

PCRQ3

ITS1Q3

IRANQ3

Abstract

Background and objectives: Strongyloides stercoralis is a nematode parasite of human with world wide distribution especially in tropical and subtropical areas. Although in most patients the infection is benign, however, in immunocompromised patients S. stercoralis can leads to hyper infection or disseminated STRONGYLOIDIASIS, which may leads to death.In respect to increasing the number of immunocompromised patients in IRAN, current study was undertook to have an understanding on STRONGYLOIDIASIS and molecular characterization of S. stercoralis in Khouzestan province which had been an endemic area for this parasite for a long time. Material and methods: During 2004-2006, a total of 200 fresh stool samples were collected from patients referred to some hospitals and diagnostic laboratories in Khouzestan and exmined for S. stercoralis.DNA was extracted from filariform larvae, obtained from agar plate culture. ITS1 region of all isolates were amplified by PCR processing.Results: 6 cases were found infected with S. stercoralis, all presenting HYPERINFECTION syndrome. Comparison of the PCR products and sequences with nucleotide sequences submitted to GenBank confirmed all 6 cases as S. stercoralis.Conclusion: This study is the first research on molecular aspects of S. stercoralis in isolates from Khouzestan province and emphasizes the health importance of this opportunistic nematode in this province and needs for further more research on this unique parasite.

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APA: Copy

NILFOROUSHAN, M.R., KIA, E.B., MIRHENDI, H., REZAEI, SASAN, MOUBEDI, I., & MARAGHI, S.. (2007). STRONGYLOIDIASIS HYPERINFECTION SYNDROME IN KHOUZESTAN PROVINCE, SOUTHWEST IRAN AND MOLECULAR CHARACTERIZATION OF ISOLATES RECOVERED FROM THE PATIENTS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 12(36), 45-48. SID. https://sid.ir/paper/52942/en

Vancouver: Copy

NILFOROUSHAN M.R., KIA E.B., MIRHENDI H., REZAEI SASAN, MOUBEDI I., MARAGHI S.. STRONGYLOIDIASIS HYPERINFECTION SYNDROME IN KHOUZESTAN PROVINCE, SOUTHWEST IRAN AND MOLECULAR CHARACTERIZATION OF ISOLATES RECOVERED FROM THE PATIENTS. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2007;12(36):45-48. Available from: https://sid.ir/paper/52942/en

IEEE: Copy

M.R. NILFOROUSHAN, E.B. KIA, H. MIRHENDI, SASAN REZAEI, I. MOUBEDI, and S. MARAGHI, “STRONGYLOIDIASIS HYPERINFECTION SYNDROME IN KHOUZESTAN PROVINCE, SOUTHWEST IRAN AND MOLECULAR CHARACTERIZATION OF ISOLATES RECOVERED FROM THE PATIENTS,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 12, no. 36, pp. 45–48, 2007, [Online]. Available: https://sid.ir/paper/52942/en

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