ANTI-ULCER AND ACUTE TOXICITY EFFECTS OF ANETHUM GRAVEOLENS L. AERIAL PARTS EXTRACTS IN MICE

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HOSSEINZADEH H.; KARIMI G.R.; AMERI MARYAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Journal of Medicinal Plants Year:2002 | Volume:1 | Issue:2 Page(s): 0-0

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Title

ANTI-ULCER AND ACUTE TOXICITY EFFECTS OF ANETHUM GRAVEOLENS L. AERIAL PARTS EXTRACTS IN MICE

Author(s)

HOSSEINZADEH H. | KARIMI G.R. | AMERI MARYAM | Issue Writer Certificate

Keywords

ANETHUM GRAVEOLENS SEED

PEPTIC ULCER

CIMETIDINE

SUCRALFATE

MUCOSE PROTECTION

Abstract

Anti-ulcer and acute toxicity effect of ANETHUM GRAVEOLENS SEED aqueous and ethanolic extracts were studied in mice. Gastric mucosal lesions were induced by oral administration of HCL (1 N) and absolute ethanol to mice. The acidity of gastric juice was measured in pyloric ligated mice. LD50 values of the aqueous and ethanolic extracts were 3.04 g/kg, i.p. (5.69, 6.16) and 6.98 g/kg, i.p. (5.69, 8.56), respectively. The efficacy of high dose of extracts (p.o.) was similar to SUCRALFATE. The acidity was reduced by the orally or intraperitoneally administration of the extracts. The results suggest that A. graveolens seed extracts have significant antisecretory and mucosal protective effects in mice

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APA: Copy

HOSSEINZADEH, H., KARIMI, G.R., & AMERI, MARYAM. (2002). ANTI-ULCER AND ACUTE TOXICITY EFFECTS OF ANETHUM GRAVEOLENS L. AERIAL PARTS EXTRACTS IN MICE. JOURNAL OF MEDICINAL PLANTS, 1(2), 0-0. SID. https://sid.ir/paper/529429/en

Vancouver: Copy

HOSSEINZADEH H., KARIMI G.R., AMERI MARYAM. ANTI-ULCER AND ACUTE TOXICITY EFFECTS OF ANETHUM GRAVEOLENS L. AERIAL PARTS EXTRACTS IN MICE. JOURNAL OF MEDICINAL PLANTS[Internet]. 2002;1(2):0-0. Available from: https://sid.ir/paper/529429/en

IEEE: Copy

H. HOSSEINZADEH, G.R. KARIMI, and MARYAM AMERI, “ANTI-ULCER AND ACUTE TOXICITY EFFECTS OF ANETHUM GRAVEOLENS L. AERIAL PARTS EXTRACTS IN MICE,” JOURNAL OF MEDICINAL PLANTS, vol. 1, no. 2, pp. 0–0, 2002, [Online]. Available: https://sid.ir/paper/529429/en

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