DETERMINATION OF HUMAN PAPILLOMA VIRUS GENOTYPES IN CERVICAL CANCER SPECIMENS, IN YAZD PROVINCE

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MAHMOUDI S.M.; HAMKAR R.; AKHAVAN TAFTI M.T.; ESLAMIFAR A.; ADIBI L.; SADRABADI A.; NATEGH R.

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Journal: Iranian Journal of Infectious Diseases and Tropical Medicine Year:2007 | Volume:12 | Issue:37 Page(s): 19-24

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Title

DETERMINATION OF HUMAN PAPILLOMA VIRUS GENOTYPES IN CERVICAL CANCER SPECIMENS, IN YAZD PROVINCE

Author(s)

Keywords

CERVICAL CANCERQ2

HUMAN PAPILLOMAVIRUS GENOTYPESQ3

Abstract

Background and objective: CERVICAL CANCER is the second most common cancer after breast cancer among women worldwide. The association between certain Human Papillomavirus (HPV) and cervical malignancy is well documented, but the rate of HPV infection and HPV genotype distribution among Iranian women still are not well known.Material and methods: In this study 40 cervical tissue specimen with different degree of malignancy were obtained from women in Yazd province and the presence of HPV genotypes were analyzed.Results: HPV DNA was detected in 75% of specimens and DNA sequencing was revealed that the genotypes 16,18,33,45 and 73 were present. HPV 16 was the most frequently observed type (70%) followed by HPV 18(16.7%), HPV 45(6.7%), HPV 33(3.3%), and HPV 73(3.3%).Conclusion: HPV infection in Iran like the other parts of the world could be the most important risk factor for the development of CERVICAL CANCER and detection and determination of HPV genotypes in conjunction with the Pap smear might be a useful method for prevention and control of CERVICAL CANCERs. In addition, determination of prevalent HPV genotypes in Iran could be utilized in production of suitable vaccines for the prevention and management of the CERVICAL CANCER.

Cites

تعیین انواع انکوژن ویروس پاپیلومای انسانی به روش PCR چندگانه در ضایعات سرطانی دهانه رحم در منطقه شمال غرب ایران

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APA: Copy

MAHMOUDI, S.M., HAMKAR, R., AKHAVAN TAFTI, M.T., ESLAMIFAR, A., ADIBI, L., SADRABADI, A., & NATEGH, R.. (2007). DETERMINATION OF HUMAN PAPILLOMA VIRUS GENOTYPES IN CERVICAL CANCER SPECIMENS, IN YAZD PROVINCE. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, 12(37), 19-24. SID. https://sid.ir/paper/52965/en

Vancouver: Copy

MAHMOUDI S.M., HAMKAR R., AKHAVAN TAFTI M.T., ESLAMIFAR A., ADIBI L., SADRABADI A., NATEGH R.. DETERMINATION OF HUMAN PAPILLOMA VIRUS GENOTYPES IN CERVICAL CANCER SPECIMENS, IN YAZD PROVINCE. IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE[Internet]. 2007;12(37):19-24. Available from: https://sid.ir/paper/52965/en

IEEE: Copy

S.M. MAHMOUDI, R. HAMKAR, M.T. AKHAVAN TAFTI, A. ESLAMIFAR, L. ADIBI, A. SADRABADI, and R. NATEGH, “DETERMINATION OF HUMAN PAPILLOMA VIRUS GENOTYPES IN CERVICAL CANCER SPECIMENS, IN YAZD PROVINCE,” IRANIAN JOURNAL OF INFECTIOUS DISEASES AND TROPICAL MEDICINE, vol. 12, no. 37, pp. 19–24, 2007, [Online]. Available: https://sid.ir/paper/52965/en

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