PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS

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ALAVIAN M.; EYN ELAHI BEHZAD; HAJARIZADEH B.; BAKHTIARI S.; NAFAR MOHSEN; AHRABI S.

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Journal: Researcher Bulletin of Medical Sciences Year:2004 | Volume:8 | Issue:5 (35) Page(s): 315-320

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Title

PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS

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Keywords

BLOOD TRANSJUSION

HEPATITIS C

HEMODIALYSIS

KIDNEY FAILURE

RISKFACTORS

Abstract

Backgrounds: HEPATITIS C virus (HCV) infection is common among patients undergoing HEMODIALYSIS. Controlling HCV-related liver diseases is an important matter of health concern among such patients. Nowadays, liver diseases are a major cause of death in patients with end stage renal disease (ESRD). Materials and methods: To investigate the prevalence of HCV infection in patients on HEMODIALYSIS and its associated risk factors, we conducted a retrospective case series of 838 patients on HEMODIALYSIS in Tehran. Patients were selected randomly (cluster sampling) and all were checked for anti-HCV antibodies, using ELISA technique and then to confirm the positive samples with RlBA.Results: Totally, 111 patients (13.2%) were infected. Considering univariate analysis, longer duration on HEMODIALYSIS (p=0.000), more weekly dialysis sessions (p=0.03), history of blood transfusion (p=0.03) and history of previous renal transplantation (p=0.01) were associated with higher rate of HCV infection. However, on multivariate analysis, HEMODIALYSIS duration (p=0.000) and blood transfusion (p=0.02) remain significant as risk factors for HCV acquisition. The more units transfused, the more the rate of HCV infection.Conclusion: It seems that early transplantation and avoidance of blood transfusion as much as possible - for example by using erithropoietin- are the two most important practical interventions to reduce HCV exposure rate in patients on HEMODIALYSIS.

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APA: Copy

ALAVIAN, M., EYN ELAHI, BEHZAD, HAJARIZADEH, B., BAKHTIARI, S., NAFAR, MOHSEN, & AHRABI, S.. (2004). PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 8(5 (35)), 315-320. SID. https://sid.ir/paper/529672/en

Vancouver: Copy

ALAVIAN M., EYN ELAHI BEHZAD, HAJARIZADEH B., BAKHTIARI S., NAFAR MOHSEN, AHRABI S.. PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2004;8(5 (35)):315-320. Available from: https://sid.ir/paper/529672/en

IEEE: Copy

M. ALAVIAN, BEHZAD EYN ELAHI, B. HAJARIZADEH, S. BAKHTIARI, MOHSEN NAFAR, and S. AHRABI, “PREVALENCE AND RISK FACTORS OF HEPATITIS C IN HEMODIALYSED PATIENTS,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 8, no. 5 (35), pp. 315–320, 2004, [Online]. Available: https://sid.ir/paper/529672/en

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