SURVEYING THE ASOCIATION BETWEEN HBS-AB AND TIME ELAPSED FOLLOWING VACCINATION IN PATIENTS WITH THALASEMIA MAJOR, BOODALI HOSPITAL, 2001

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DARYANI F.; SHARIFI M.; VAHIDSHAHI K.

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Journal: Researcher Bulletin of Medical Sciences Year:2003 | Volume:8 | Issue:3 (33) Page(s): 203-206

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Title

SURVEYING THE ASOCIATION BETWEEN HBS-AB AND TIME ELAPSED FOLLOWING VACCINATION IN PATIENTS WITH THALASEMIA MAJOR, BOODALI HOSPITAL, 2001

Author(s)

DARYANI F. | SHARIFI M. | VAHIDSHAHI K. | Issue Writer Certificate

Keywords

THALASEMIA MAJOR

HEPATITIS B

VACCINATION

Abstract

Background: HEPATITIS B is a major problem occurred in patients with THALASEMIA MAJOR due to repeated blood transfusion. Regarding its acute (fulminant hepatitis) and chronic (cirrhosis, hepatic neoplasm) complications, VACCINATION could be helpful. As time elapsed, the antibody level is diminished. The present study was conducted to define the exact time of booster VACCINATION to be generalized as a uniform guideline for thalasemic patients. Materials and Methods: For this historical cohort study, 50 patients with THALASEMIA MAJOR and 50 normal subjects who have received HEPATITIS B vaccine were selected. HBS-Ab was determined using ELISA technique. Then, reduced antibody level was judged with elapsed following VACCINATION. Results: In the normal subjects, 8 years following the VACCINATION, there exist a suitable level of antibody (99.5±5 U/l), however, in the case group, those who have received vaccine within the recent 7 years have still suitable level of antibody (90±5 U/l), but others (time elapsed following VACCINATION was greater than 7 years) lacked sufficient level of antibody (12.5±2.5 U/l) (P<0.01). Conclusion: We recommend determining the antibody level 7 years following the initial VACCINATION in patients with THALASEMIA MAJOR, so that if sufficient level is absent, booster VACCINATION should be applied.

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APA: Copy

DARYANI, F., SHARIFI, M., & VAHIDSHAHI, K.. (2003). SURVEYING THE ASOCIATION BETWEEN HBS-AB AND TIME ELAPSED FOLLOWING VACCINATION IN PATIENTS WITH THALASEMIA MAJOR, BOODALI HOSPITAL, 2001. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 8(3 (33)), 203-206. SID. https://sid.ir/paper/530303/en

Vancouver: Copy

DARYANI F., SHARIFI M., VAHIDSHAHI K.. SURVEYING THE ASOCIATION BETWEEN HBS-AB AND TIME ELAPSED FOLLOWING VACCINATION IN PATIENTS WITH THALASEMIA MAJOR, BOODALI HOSPITAL, 2001. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2003;8(3 (33)):203-206. Available from: https://sid.ir/paper/530303/en

IEEE: Copy

F. DARYANI, M. SHARIFI, and K. VAHIDSHAHI, “SURVEYING THE ASOCIATION BETWEEN HBS-AB AND TIME ELAPSED FOLLOWING VACCINATION IN PATIENTS WITH THALASEMIA MAJOR, BOODALI HOSPITAL, 2001,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 8, no. 3 (33), pp. 203–206, 2003, [Online]. Available: https://sid.ir/paper/530303/en

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