PREVALENCE OF OPEN ANGLE GLAUCOMA, GLAUCOMA SUSPECT AND OCULAR HYPERTENSION IN THYROID-RELATED IMMUNE ORBITOPATHY

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BEHROUZI Z.; MOHAMMAD RABI H.; AZIZI F.; DAFTARIAN N.; MEHRABI YAD ELAH; ARDESHIRI M.; MOHAMMADPOUR M.

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Journal: JOURNAL OF CURRENT OPHTHALMOLOGY Year:2005 | Volume:18 | Issue:4 Page(s): 61-67

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Title

PREVALENCE OF OPEN ANGLE GLAUCOMA, GLAUCOMA SUSPECT AND OCULAR HYPERTENSION IN THYROID-RELATED IMMUNE ORBITOPATHY

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Keywords

THYROID-RELATED IMMUNE ORBITOPATHYQ4

OCULAR HYPERTENSIONQ4

GLAUCOMA SUSPECTQ4

OPEN ANGLE GLAUCOMAQ4

Abstract

Purpose: To determine the prevalence of open-angle glaucoma (OAG), GLAUCOMA SUSPECTs (GS), and OCULAR HYPERTENSION (OHT) in patients with THYROID-RELATED IMMUNE ORBITOPATHY (TRIO) and compare it with a control group.Patients & Methods: In this cross-sectional analytic study, 233 eyes of 117 patients with TRIO (case group) and 240 eyes of 120 normal age and sex-matched individuals (control group) underwent complete ocular examinations.Grave's orbitopathy was diagnosed by clinical examinations with the help of an endocrinologist and paraclinical tests. Controls were selected among apparently healthy individuals with no history of previous orbitopathy or thyroid diseases.Results: Prevalence of OAG, and OHT was 2.5% and 8.5% in the case group, respectively. In contrast, OAG was detected in only 2 eyes (0.8%) of the control group and there were no instances of GS or OHT in the control group. Although the prevalence of OAG and GS were higher in cases than controls, this difference was not statistically significant. However, OHT was more common in cases (P<0.01). Ten eyes in the case group (4.3%) developed compressive optic neuropathy (CON); high intraocular pressure (lOP) was detected in 5 of them (2.1%). All cases of OAG and GS in the case group were classified as stage 3 or higher of NOSPECS (No symptoms or signs, Only signs no symptoms, Soft tissue, Proptosis, Extraocular muscle, Cornea, Sight loss). Active Grave's orbitopathy was only more prevalent in patients with OHT (P<0.001).Conclusion: The prevalence of OHT was higher in cases with Grave's orbitopathy than age and sex matched controls. Ophthalmologic examinations including lOP measurement (and if needed automated visual fields) should be regularly performed in patients with Graves orbitopathy particularly in higher stages and those with active disease.

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APA: Copy

BEHROUZI, Z., MOHAMMAD RABI, H., AZIZI, F., DAFTARIAN, N., MEHRABI, YAD ELAH, ARDESHIRI, M., & MOHAMMADPOUR, M.. (2005). PREVALENCE OF OPEN ANGLE GLAUCOMA, GLAUCOMA SUSPECT AND OCULAR HYPERTENSION IN THYROID-RELATED IMMUNE ORBITOPATHY. JOURNAL OF CURRENT OPHTHALMOLOGY, 18(4), 61-67. SID. https://sid.ir/paper/53070/en

Vancouver: Copy

BEHROUZI Z., MOHAMMAD RABI H., AZIZI F., DAFTARIAN N., MEHRABI YAD ELAH, ARDESHIRI M., MOHAMMADPOUR M.. PREVALENCE OF OPEN ANGLE GLAUCOMA, GLAUCOMA SUSPECT AND OCULAR HYPERTENSION IN THYROID-RELATED IMMUNE ORBITOPATHY. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2005;18(4):61-67. Available from: https://sid.ir/paper/53070/en

IEEE: Copy

Z. BEHROUZI, H. MOHAMMAD RABI, F. AZIZI, N. DAFTARIAN, YAD ELAH MEHRABI, M. ARDESHIRI, and M. MOHAMMADPOUR, “PREVALENCE OF OPEN ANGLE GLAUCOMA, GLAUCOMA SUSPECT AND OCULAR HYPERTENSION IN THYROID-RELATED IMMUNE ORBITOPATHY,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 18, no. 4, pp. 61–67, 2005, [Online]. Available: https://sid.ir/paper/53070/en

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