ROLE OF PROPHYLACTIC INTRACAMERAL R-TPA IN PREVENTION OF FIBRINOUS REACTION AFTER CONGENITAL CATARACT SURGERY WITH IOL IMPLANTATION: A DOUBLE-MASKED RANDOMIZED CLINICAL TRIAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

PIRI N.; SIATIRI H.; ASGHARI H.; BEHBAHANI NEJAD M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF CURRENT OPHTHALMOLOGY Year:2004 | Volume:17 | Issue:2 Page(s): 76-82

Download Full-Text

Persian Verion

View:

767

Download:

Cites:

Information Journal Paper

Title

ROLE OF PROPHYLACTIC INTRACAMERAL R-TPA IN PREVENTION OF FIBRINOUS REACTION AFTER CONGENITAL CATARACT SURGERY WITH IOL IMPLANTATION: A DOUBLE-MASKED RANDOMIZED CLINICAL TRIAL

Author(s)

PIRI N. | SIATIRI H. | ASGHARI H. | BEHBAHANI NEJAD M. | Issue Writer Certificate

Keywords

CONGENITAL CATARACTQ4

FIBRINOUS EFFUSIONQ4

INTRACAMERALLNJECTIONQ4

PROPHYLAXISQ4

R-TPAQ4

Abstract

Purpose: To evaluate the efficacy of intracameral recombinant tissue plasminogen activator in prevention of FIBRINOUS EFFUSION after lensectomy, anterior vitrectomy and PC IOL implantation in patients with CONGENITAL CATARACT. Methods: The study was done as a double-masked randomized clinical trial. Between April 2002 and Nov 2003, 34 eyes from 26 patients with CONGENITAL CATARACT were included in the study and randomized into two groups (18 cases & 16 controls). Each eye underwent lensectomy and anterior vitrectomy with PC IOL implantation. At the end of surgery 20 μg R-TPA was injected intracamerally in case group. No injection was done in control group. All patients received periocular, systemic and topical steroids after surgery. Follow up examinations were done in the following 3 months.Results: The incidence of intraocular fibrin membrane formation was significantly lower in case group on days 1 (P=0.024), 3 (p=0.01), 7 (P=0.01), 14 (P=0.01); but there was no significant difference on days 30 and 90. The frequency of pigmented IOL precipitates were significantly lower in case group at the end of third month (P<0.001). No gross ocular side effects were noted after R-TPA injection.Conclusion: It seems that prophylactic intracameral R-TPA is effective in prevention of FIBRINOUS EFFUSION at least in the first two weeks after cataract extraction in pediatric age group and decreases incidence of pigmented IOL precipitates.

Cites

No record.

References

No record.

Cite

APA: Copy

ASGHARI, H., SIATIRI, H., PIRI, N., & BEHBAHANI NEJAD, M.. (2004). ROLE OF PROPHYLACTIC INTRACAMERAL R-TPA IN PREVENTION OF FIBRINOUS REACTION AFTER CONGENITAL CATARACT SURGERY WITH IOL IMPLANTATION: A DOUBLE-MASKED RANDOMIZED CLINICAL TRIAL. JOURNAL OF CURRENT OPHTHALMOLOGY, 17(2), 76-82. SID. https://sid.ir/paper/53122/en

Vancouver: Copy

ASGHARI H., SIATIRI H., PIRI N., BEHBAHANI NEJAD M.. ROLE OF PROPHYLACTIC INTRACAMERAL R-TPA IN PREVENTION OF FIBRINOUS REACTION AFTER CONGENITAL CATARACT SURGERY WITH IOL IMPLANTATION: A DOUBLE-MASKED RANDOMIZED CLINICAL TRIAL. JOURNAL OF CURRENT OPHTHALMOLOGY[Internet]. 2004;17(2):76-82. Available from: https://sid.ir/paper/53122/en

IEEE: Copy

H. ASGHARI, H. SIATIRI, N. PIRI, and M. BEHBAHANI NEJAD, “ROLE OF PROPHYLACTIC INTRACAMERAL R-TPA IN PREVENTION OF FIBRINOUS REACTION AFTER CONGENITAL CATARACT SURGERY WITH IOL IMPLANTATION: A DOUBLE-MASKED RANDOMIZED CLINICAL TRIAL,” JOURNAL OF CURRENT OPHTHALMOLOGY, vol. 17, no. 2, pp. 76–82, 2004, [Online]. Available: https://sid.ir/paper/53122/en

Related Journal Papers