COMPARISON OF LITHIUM CARBONATE AND PYRIDOXINE IN THE TREATMENT OF LATE LUTEAL PHASE DYSPHORIC DISORDER (LLPDD)

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ZAHIR ALDIN A.R.; JARIANI M.

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Journal: Iranian Journal of Forensic Medicine Year:2003 | Volume:9 | Issue:30 Page(s): 65-68

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Title

COMPARISON OF LITHIUM CARBONATE AND PYRIDOXINE IN THE TREATMENT OF LATE LUTEAL PHASE DYSPHORIC DISORDER (LLPDD)

Author(s)

ZAHIR ALDIN A.R. | JARIANI M. | Issue Writer Certificate

Keywords

LATE LUTEAL PHASE DYSPHORIC DISORDER (LLPDD)Q4

LITHIUMQ4

PYRIDOXINEQ4

Abstract

Background: Late luteal phase dysphoric disorder (LLPDD) is among the most common psychiatric problems within female population. There have been several different suggestions for its treatment with nebulous results. Present study, which was conducted in Iman Hossein hospital compares the efficacy of LITHIUM carbonate and PYRIDOXINE the LLPDD aiming at treating premenstrual syndrome. Methods: Regarding DSM IV Criteria, fifty patients were included in this cross over clinical trial study. Studied population was divided into two different groups and was randomly treated for three consecutive menstrual cycles with one of the following regiments: PYRIDOXINE (100-200 mg/day) or LITHIUM (600 mg/day), each for seven days. Patients in each group were assessed for premenstrual symptoms with LLPDD checklist based on DSM-IV for these three months. After being drug free for a month, all patients received the second drug. Results: This research showed drug effect in premenstrual syndrome improvement (63.8 percent for LITHIUM therapy Vs 48.1 Percent for PYRIDOXINE therapy), especially in moods symptoms (98.7 percent for LITHIUM therapy compared 49.4 percent for PYRIDOXINE therapy).Conclusion: Comparing with PYRIDOXINE, LITHIUM is more effective in reducing the general symptoms of the luteal phase, especially mood symptoms (p value<0.05). No significant side effect of LITHIUM was observed in this study.

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APA: Copy

ZAHIR ALDIN, A.R., & JARIANI, M.. (2003). COMPARISON OF LITHIUM CARBONATE AND PYRIDOXINE IN THE TREATMENT OF LATE LUTEAL PHASE DYSPHORIC DISORDER (LLPDD). SCIENTIFIC JOURNAL OF FORENSIC MEDICINE, 9(30), 65-68. SID. https://sid.ir/paper/53561/en

Vancouver: Copy

ZAHIR ALDIN A.R., JARIANI M.. COMPARISON OF LITHIUM CARBONATE AND PYRIDOXINE IN THE TREATMENT OF LATE LUTEAL PHASE DYSPHORIC DISORDER (LLPDD). SCIENTIFIC JOURNAL OF FORENSIC MEDICINE[Internet]. 2003;9(30):65-68. Available from: https://sid.ir/paper/53561/en

IEEE: Copy

A.R. ZAHIR ALDIN, and M. JARIANI, “COMPARISON OF LITHIUM CARBONATE AND PYRIDOXINE IN THE TREATMENT OF LATE LUTEAL PHASE DYSPHORIC DISORDER (LLPDD),” SCIENTIFIC JOURNAL OF FORENSIC MEDICINE, vol. 9, no. 30, pp. 65–68, 2003, [Online]. Available: https://sid.ir/paper/53561/en

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