AUTOIMMUNE THYROID DISORDERS IN PATIENTS WITH DIABETES TYPE 1

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ARDESHIR LARIJANI MOHAMMAD BAGHER; YAR AHMADI SH.; JAVADI E.; SHOUSHTARIZADEH P.; AKHAVAN HEJAZI S.M.; GHOLAMPOUR DEHAKI M.

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Journal: Iranian Journal of Diabetes and Metabolism Year:2003 | Volume:2 | Issue:2 Page(s): 111-115

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Title

AUTOIMMUNE THYROID DISORDERS IN PATIENTS WITH DIABETES TYPE 1

Author(s)

Keywords

DIABETES TYPE 1Q3

AUTOIMMUNE THYROIDITISQ4

ANTI-THYROID ANTIBODIESQ4

Abstract

Background: DIABETES TYPE 1 is characterized by autoimmune destruction or primary dysfunction of pancreatic β cells. The more common form is the autoimmune type, which can be associated with other endocrine malfunction such as adrenal insufficiency and Hashimoto' s thyroiditis. AUTOIMMUNE THYROIDITIS is characterized by presence of anti TG, anti TPO and anti TSH antibodies in the plasma. This study has investigated the prevalence of autoimmune thyroid disorders in type 1 diabetic patients. Methods: 200 type 1 diabetics and 200 age/sex matched non-diabetic controls were recruited. Blood samples were taken to determine serum levels of thyroid hormones (T3RU, T3, T4, and TSH) and antithyroid antibodies. Results: TG-Ab and TPO-Ab levels were significantly higher (P<0.001) in diabetics compared to controls (mean TG-Ab: 955.7±495.5in diabetics and 451.0±189.5in controls; mean TPO-Ab: 463.2±182.3in diabetics and 112.4±38.3in controls). Clinical and subclinical hyperthyroidism was four times more common in diabetics. Conclusion: It seems reasonable that type 1 diabetic patients, especially those at younger ages, be screened for thyroid hormones and ANTI-THYROID ANTIBODIES.

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References

EPIDEMIOLOGY OF DIABETES MELLITUS IN IRAN

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APA: Copy

ARDESHIR LARIJANI, MOHAMMAD BAGHER, YAR AHMADI, SH., JAVADI, E., SHOUSHTARIZADEH, P., AKHAVAN HEJAZI, S.M., & GHOLAMPOUR DEHAKI, M.. (2003). AUTOIMMUNE THYROID DISORDERS IN PATIENTS WITH DIABETES TYPE 1. JOURNAL OF DIABETES AND METABOLIC DISORDERS, 2(2), 111-115. SID. https://sid.ir/paper/53855/en

Vancouver: Copy

ARDESHIR LARIJANI MOHAMMAD BAGHER, YAR AHMADI SH., JAVADI E., SHOUSHTARIZADEH P., AKHAVAN HEJAZI S.M., GHOLAMPOUR DEHAKI M.. AUTOIMMUNE THYROID DISORDERS IN PATIENTS WITH DIABETES TYPE 1. JOURNAL OF DIABETES AND METABOLIC DISORDERS[Internet]. 2003;2(2):111-115. Available from: https://sid.ir/paper/53855/en

IEEE: Copy

MOHAMMAD BAGHER ARDESHIR LARIJANI, SH. YAR AHMADI, E. JAVADI, P. SHOUSHTARIZADEH, S.M. AKHAVAN HEJAZI, and M. GHOLAMPOUR DEHAKI, “AUTOIMMUNE THYROID DISORDERS IN PATIENTS WITH DIABETES TYPE 1,” JOURNAL OF DIABETES AND METABOLIC DISORDERS, vol. 2, no. 2, pp. 111–115, 2003, [Online]. Available: https://sid.ir/paper/53855/en

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