DENOUEMENT CONTINUED FROM PAGE 12

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PANAHI M.

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Journal Paper

Paper Information

Journal: Medical Journal of Mashhad University of Medical Sciences Year:2003 | Volume:46 | Issue:79 Page(s): 83-86

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Title

DENOUEMENT CONTINUED FROM PAGE 12

Author(s)

PANAHI M. | Issue Writer Certificate

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Abstract

For patient, assay of hydrogen peroxide production (Nitroblue tetrazolium reduction) was done, and NBT test was positive. So diagnosis of chronic granulomatous disease (CGD) confirmed. Cephalotin therapy continued, gingivostomatitis subsided, fever and headache disappeared and patient with prophylactic dosage of co-trimoxazol discharged.CGD of childhood is a rare group of inherited disorders phagocytic cells (6) characterized clinically by recurrent life-threatening infections and excessive granuloma formation.Phagocytosis and migration of phagocytes are normal, but killing of microorganisms because of defective of hydrogen peroxide, is impaired (1,2,6). The current mortality rate is 2-5 percent per year. Patients with CGD in the absence of antibiotic proplylaxis have severed infections due to catalase + tive bacteria and fungi about once a year (6), but proplylaxis with co-trimoxazole reduces. The incidence of serious bacterial infection to about one every four years (6) interferon gamma prophylaxis has reduced bacterial infections by an additional 70 percent (6).Fungal infestations in spite of antibiotic and gamma interferon proplylaxis remain a major problem with an incidence of approximately 0.1 infection per patients per year (6). Although these patients are already somewhat immunocompromised, the judicious use of corticosteroids in conjunction with antibiotics has been (1) successful in opening and maintaining the patency of hollow visci in patients with CGD (4,5).

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APA: Copy

PANAHI, M.. (2003). DENOUEMENT CONTINUED FROM PAGE 12. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 46(79), 83-86. SID. https://sid.ir/paper/542911/en

Vancouver: Copy

PANAHI M.. DENOUEMENT CONTINUED FROM PAGE 12. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2003;46(79):83-86. Available from: https://sid.ir/paper/542911/en

IEEE: Copy

M. PANAHI, “DENOUEMENT CONTINUED FROM PAGE 12,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 46, no. 79, pp. 83–86, 2003, [Online]. Available: https://sid.ir/paper/542911/en

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