ACUTE BRUCELLOSIS WITH PANCYTOPENIA AND MACULOPAPULAR RASH (CASE REPORT)

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OMIDI ABAS ALI; JAFARIAN AMIR HOSSEIN; ERFANIAN M.; YAZDANPANAH MOHAMMAD JAVAD; SHARIFIAN MASOUD

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Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF PATHOLOGY (IJP) Year:2009 | Volume:4 | Issue:3 Page(s): 133-136

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Title

ACUTE BRUCELLOSIS WITH PANCYTOPENIA AND MACULOPAPULAR RASH (CASE REPORT)

Author(s)

Keywords

BRUCELLOSIS

PANCYTOPENIAS

SKIN RASH

IRAN

Abstract

Human BRUCELLOSIS is common in developing countries and is a multi-system disease with a broad spectrum of clinical manifestations. Cutaneous lesions associated with BRUCELLOSIS have been rarely reported in the literature. Here we present a case of a 32-year-old man with history of consumption of cheese made from raw milk seen with occurrence of pancytopenia and diffuse maculopapular rash during the course of Brucella infection. Physical examination showed fever, splenomegaly, mild hepatomegaly and pruritic maculopapular exanthema over the trunk, arms and legs. Laboratory tests revealed pancytopenia. Parasitic examinations and serologic tests for syphilis, salmonellosis, rickettsiasis, toxoplasmosis, Epstein-Barr virus, human immunodeficiency virus, and hepatitis B and C viruses were negative. There was no history of drug consumption.The Brucella agglutination test titer was 1/1280 and histological examination of skin biopsy showed lymphohistiocytic perivascular infiltrates in the upper dermis.Lesions were interpreted as Brucellar dermatitis, The patient was subsequently treated with oral doxycycline and rifampin and was discharged in good health. If there is suspicion of exposure to infected food products, BRUCELLOSIS should be included in the differential diagnosis of pancytopenia in Brucella-endemic areas; there may be skin lesions other than purpura that can accompany thrombocytopenia.

Cites

SKIN RASHES ON LEG IN BRUCELLOSIS: A RARE PRESENTATION (CASE REPORT)

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APA: Copy

OMIDI, ABAS ALI, JAFARIAN, AMIR HOSSEIN, ERFANIAN, M., YAZDANPANAH, MOHAMMAD JAVAD, & SHARIFIAN, MASOUD. (2009). ACUTE BRUCELLOSIS WITH PANCYTOPENIA AND MACULOPAPULAR RASH (CASE REPORT). IRANIAN JOURNAL OF PATHOLOGY (IJP), 4(3), 133-136. SID. https://sid.ir/paper/550754/en

Vancouver: Copy

OMIDI ABAS ALI, JAFARIAN AMIR HOSSEIN, ERFANIAN M., YAZDANPANAH MOHAMMAD JAVAD, SHARIFIAN MASOUD. ACUTE BRUCELLOSIS WITH PANCYTOPENIA AND MACULOPAPULAR RASH (CASE REPORT). IRANIAN JOURNAL OF PATHOLOGY (IJP)[Internet]. 2009;4(3):133-136. Available from: https://sid.ir/paper/550754/en

IEEE: Copy

ABAS ALI OMIDI, AMIR HOSSEIN JAFARIAN, M. ERFANIAN, MOHAMMAD JAVAD YAZDANPANAH, and MASOUD SHARIFIAN, “ACUTE BRUCELLOSIS WITH PANCYTOPENIA AND MACULOPAPULAR RASH (CASE REPORT),” IRANIAN JOURNAL OF PATHOLOGY (IJP), vol. 4, no. 3, pp. 133–136, 2009, [Online]. Available: https://sid.ir/paper/550754/en

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