SYNTHESIS, CHARACTERIZATION, AND DRUG RELEASE BEHAVIOUR OF NOVEL SOY PROTEIN/POLY(ACRYLIC ACID) IPN HY-DROGELS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

LIU Y.; CUI Y.; YIN G.; MA H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Polymer Journal Year:2009 | Volume:18 | Issue:4 (106) Page(s): 339-348

Download Full-Text

View:

842

Download:

470

Cites:

Information Journal Paper

Title

SYNTHESIS, CHARACTERIZATION, AND DRUG RELEASE BEHAVIOUR OF NOVEL SOY PROTEIN/POLY(ACRYLIC ACID) IPN HY-DROGELS

Author(s)

LIU Y. | CUI Y. | YIN G. | MA H. | Issue Writer Certificate

Keywords

SOY PROTEIN

ACRYLIC ACID

DRUG DELIVERY SYSTEMS

HYDROGELS

COLON

Abstract

A series of novel interpenetrating polymer network (IPN) HYDROGELS based on SOY PROTEIN (SP) and poly(acrylic acid) (PAA) were prepared with glutaraldehyde and N,N¢-methylenebisacrylamide (BIS) as the cross-linking agents. The structure and properties of the IPN HYDROGELS were characterized by FTIR, SEM, and DSC. The effects of pH and SP and BIS contents on the behaviour and release mechanism of the model drug bovine serum albumin (BSA) were also investigated in detail. The FTIR data indicated that the absorption of BSA into the IPN HYDROGELS is purely physical process. The SEM showed that changing the content of SP or BIS can influence the pore size and pore wall thickness of the HYDROGELS. The DSC data signify that all the HYDROGELS had good compatibility and miscibility, as well. It was also found that the release profiles of BSA strongly are dependent on the value of pH. The release percentage of BSA decreased with increasing the contents of SP or BIS. The BSA release profile followed Fickian diffusion pattern at pH below the pKa of PAA and the non- Fickian diffusion at pH above the pKa of PAA. The results showed that the IPN HYDROGELS are suitable candidates for COLON drug delivery.

Cites

OPTIMIZED SYNTHESIS OF LIGNOSULPHONATE-GPOLY (ACRYLIC ACID-CO-ACRYLAMIDE) SUPERABSORBENT HYDROGEL BASED ON THE TAGUCHI METHOD

References

No record.

Cite

APA: Copy

LIU, Y., CUI, Y., YIN, G., & MA, H.. (2009). SYNTHESIS, CHARACTERIZATION, AND DRUG RELEASE BEHAVIOUR OF NOVEL SOY PROTEIN/POLY(ACRYLIC ACID) IPN HY-DROGELS. IRANIAN POLYMER JOURNAL (ENGLISH), 18(4 (106)), 339-348. SID. https://sid.ir/paper/562742/en

Vancouver: Copy

LIU Y., CUI Y., YIN G., MA H.. SYNTHESIS, CHARACTERIZATION, AND DRUG RELEASE BEHAVIOUR OF NOVEL SOY PROTEIN/POLY(ACRYLIC ACID) IPN HY-DROGELS. IRANIAN POLYMER JOURNAL (ENGLISH)[Internet]. 2009;18(4 (106)):339-348. Available from: https://sid.ir/paper/562742/en

IEEE: Copy

Y. LIU, Y. CUI, G. YIN, and H. MA, “SYNTHESIS, CHARACTERIZATION, AND DRUG RELEASE BEHAVIOUR OF NOVEL SOY PROTEIN/POLY(ACRYLIC ACID) IPN HY-DROGELS,” IRANIAN POLYMER JOURNAL (ENGLISH), vol. 18, no. 4 (106), pp. 339–348, 2009, [Online]. Available: https://sid.ir/paper/562742/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops