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Information Journal Paper

Title

QNR PREVALENCE IN EXTENDED SPECTRUM BETA-LACTAMASES (ESBLS) AND NONE-ESBLS PRODUCING ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS IN CENTRAL OF IRAN

Pages

  458-464

Abstract

 Objective (s): Extensive use of quinolones has been associated with raising level of RESISTANCE. In the current, we focused on assessing the prevalence ofEscherichia coli RESISTANCE to quinolones and frequency of qnrA, qnrB and qnrS in non ESBLs (extended spectrum beta-lactamases) and ESBLs producing E. coli with blaSHV and blaTEM.Materials and Methods: One hundred and fiftyE. coli isolates were identified during Mar.2007 to Apr.2008 in Milad (Tehran) hospital. They were tested for ESBLs production as well as quinolone RESISTANCE. PCR was performed for detection of blaSHV and blaTEM as well as qnrA, B and S.Results: Of 150 isolates, forty-two (28%) ESBLs producing and one hundred and eight (72%) non-ESBLs producing E. coliwere identified.64.2% (n=24) of E. coli producing ESBLs and 4.62% (n=5) of non-ESBLs E. coli were RESISTANCE to CIPROFLOXACIN.95.2% (n=40) and 26.1% (n=11) of the isolates harbored blaTEM and blaSHV, respectively.23.8% (n=10) had both genes.37.5% (n=9) and 20.8% (n=4) of ESBLs producing E. coliwere positive for qnrA and qnrB respectively. qnrS was not identified in any isolate.Conclusion: Our study showed high frequency of ESBLs producingE. coli as well as quinolone RESISTANCE genes (qnrA, qnrB) in Milad hospital.

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    APA: Copy

    PAKZAD, IRAJ, GHAFOURIAN, SOHBHAN, TAHERIKALANI, MOROVAT, SADEGHIFARD, NORKHODA, ABTAHI, HAMID, RAHBAR, MOHAMMAD, & MANSORY JAMSHIDI, NEDA. (2011). QNR PREVALENCE IN EXTENDED SPECTRUM BETA-LACTAMASES (ESBLS) AND NONE-ESBLS PRODUCING ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS IN CENTRAL OF IRAN. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 14(5 (52)), 458-464. SID. https://sid.ir/paper/569608/en

    Vancouver: Copy

    PAKZAD IRAJ, GHAFOURIAN SOHBHAN, TAHERIKALANI MOROVAT, SADEGHIFARD NORKHODA, ABTAHI HAMID, RAHBAR MOHAMMAD, MANSORY JAMSHIDI NEDA. QNR PREVALENCE IN EXTENDED SPECTRUM BETA-LACTAMASES (ESBLS) AND NONE-ESBLS PRODUCING ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS IN CENTRAL OF IRAN. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2011;14(5 (52)):458-464. Available from: https://sid.ir/paper/569608/en

    IEEE: Copy

    IRAJ PAKZAD, SOHBHAN GHAFOURIAN, MOROVAT TAHERIKALANI, NORKHODA SADEGHIFARD, HAMID ABTAHI, MOHAMMAD RAHBAR, and NEDA MANSORY JAMSHIDI, “QNR PREVALENCE IN EXTENDED SPECTRUM BETA-LACTAMASES (ESBLS) AND NONE-ESBLS PRODUCING ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTIONS IN CENTRAL OF IRAN,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 14, no. 5 (52), pp. 458–464, 2011, [Online]. Available: https://sid.ir/paper/569608/en

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