COMPARISON OF THE EFFICACY OF FLUCONAZOLE AND GRISEOFULVIN IN TINEA CAPITIS

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DASTGHEYB L.; AZIZZADEH A.; JAFARI P.

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Journal: Iranian Journal of Dermatology Year:2005 | Volume:8 | Issue:2 Page(s): 88-92

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Information Journal Paper

Title

COMPARISON OF THE EFFICACY OF FLUCONAZOLE AND GRISEOFULVIN IN TINEA CAPITIS

Author(s)

DASTGHEYB L. | AZIZZADEH A. | JAFARI P. | Issue Writer Certificate

Keywords

FLUCONAZOLEQ4

GRISEOFULVINQ4

TINEA CAPITISQ4

TREATMENTQ3

Abstract

Background: TINEA CAPITIS is a relatively common fungal in children. infection Although several oral antifungal agents have been used in the TREATMENT of TINEA CAPITIS, griseofulvin has been considered as the treatment of choice for a long time. Objective: To compare the therapeutic effects of FLUCONAZOLE with GRISEOFULVIN on tinea capitis. Patients Methods: Through and randomized, single-blinded, clinical trial on 40 clinically suspected and mycologically confirmed TINEA CAPITIS cases, 19 cases received oral FLUCONAZOLE for 4 weeks and 21 patients were treated with GRISEOFULVIN for 6 weeks. All patients were evaluated clinically and mycologically before receiving their treatment and 8 weeks after the begining of treatment. Results: The age range of the patients was from 1 to 16 years. Thirty-two cases were males. Mycology studies indicated that the causative agents were Trichophyton verrucosum in 16 cases, Trichophyton violaceum in 16 cases and Microporum canis in 8 cases. At the end of the eighth week of the begining of TREATMENT, 15 cases were cured in the FLUCONAZOLE group compared with 16 cases in the GRISEOFULVIN group (P>0.05). a Conclusion: It seems that GRISEOFULVIN could be still considered as the first choice drug in the TREATMENT of TINEA CAPITIS and FLUCONAZOLE could be used as an alternative drug.

Cites

A COMPARISON OF THE EFFICACY OF FLUCONAZOL AND GRISEOFULVIN IN TINEA CRURIS: A SINGLE BLIND CLINICAL TRIAL STUDY

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APA: Copy

DASTGHEYB, L., AZIZZADEH, A., & JAFARI, P.. (2005). COMPARISON OF THE EFFICACY OF FLUCONAZOLE AND GRISEOFULVIN IN TINEA CAPITIS. IRANIAN JOURNAL OF DERMATOLOGY, 8(2), 88-92. SID. https://sid.ir/paper/57910/en

Vancouver: Copy

DASTGHEYB L., AZIZZADEH A., JAFARI P.. COMPARISON OF THE EFFICACY OF FLUCONAZOLE AND GRISEOFULVIN IN TINEA CAPITIS. IRANIAN JOURNAL OF DERMATOLOGY[Internet]. 2005;8(2):88-92. Available from: https://sid.ir/paper/57910/en

IEEE: Copy

L. DASTGHEYB, A. AZIZZADEH, and P. JAFARI, “COMPARISON OF THE EFFICACY OF FLUCONAZOLE AND GRISEOFULVIN IN TINEA CAPITIS,” IRANIAN JOURNAL OF DERMATOLOGY, vol. 8, no. 2, pp. 88–92, 2005, [Online]. Available: https://sid.ir/paper/57910/en

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