ASSOCIATION BETWEEN CANCER AND SERUM ADIPONECTIN LEVEL: THE REVIEW OF EPIDEMIOLOGIC EVIDENCES

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IZADI V.; AZADBAKHT L.

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Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2014 | Volume:15 | Issue:5 Page(s): 97-110

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Title

ASSOCIATION BETWEEN CANCER AND SERUM ADIPONECTIN LEVEL: THE REVIEW OF EPIDEMIOLOGIC EVIDENCES

Author(s)

IZADI V. | AZADBAKHT L. | Issue Writer Certificate

Keywords

ADIPONECTINQ2

CANCERQ3

CELL PROLIFERATIONQ2

MALIGNANCYQ2

Abstract

Background and aims: ADIPONECTIN, an adipose tissue derived adipokines, has anti-inflammatory, anti-obesity and anti-diabetic properties. There are several studies investigated the association between this hormone and different types of CANCER. In present research, the study aimed to review the relationship between ADIPONECTIN and CANCERs.Methods: In this review study, various articles as following: case control, cross sectional and longitudinal studies have been found through PubMed database from 2002 to October 2011, by using the following key words: CANCER, MALIGNANCY, CELL PROLIFERATION and ADIPONECTIN.Result: From the total number of 45 articles, evidences proved the inverse association between the hormone and the risk of breast CANCER, in which has been shown both cohort and case-control studies, in pre- and post- menopausal women. Endometrial CANCER risk was significantly lower in women with higher plasma ADIPONECTIN level compared to women with lower level of hormone.Risk of benign prostate hyperplasia and prostate CANCER were higher in men with lower level of ADIPONECTIN concentration. Studies have shown the inverse correlation between the mentioned hormone and risk of colorectal CANCER. Also, it seems that ADIPONECTIN inversely associates with pancreatic CANCER in men.Conclusion: It seems that serum ADIPONECTIN level has inversely associated with risk of several CANCERs; this hormone suppresses the growth and proliferation of CANCER cells, direct or indirect, via several mechanisms.

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APA: Copy

IZADI, V., & AZADBAKHT, L.. (2014). ASSOCIATION BETWEEN CANCER AND SERUM ADIPONECTIN LEVEL: THE REVIEW OF EPIDEMIOLOGIC EVIDENCES. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 15(5), 97-110. SID. https://sid.ir/paper/58580/en

Vancouver: Copy

IZADI V., AZADBAKHT L.. ASSOCIATION BETWEEN CANCER AND SERUM ADIPONECTIN LEVEL: THE REVIEW OF EPIDEMIOLOGIC EVIDENCES. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;15(5):97-110. Available from: https://sid.ir/paper/58580/en

IEEE: Copy

V. IZADI, and L. AZADBAKHT, “ASSOCIATION BETWEEN CANCER AND SERUM ADIPONECTIN LEVEL: THE REVIEW OF EPIDEMIOLOGIC EVIDENCES,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 5, pp. 97–110, 2014, [Online]. Available: https://sid.ir/paper/58580/en

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