SYNTHESIS AND FORMULATION OF DIMETHYL PHTHALATE AS AN INSECT REPELLENT

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AKBARY J.; ASKARI-RAD H.; EBRAHIMIZADEH M.A.; KOZEHGAR-
KALEDGI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2004 | Volume:6 | Issue:1 Page(s): 37-42

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Information Journal Paper

Title

SYNTHESIS AND FORMULATION OF DIMETHYL PHTHALATE AS AN INSECT REPELLENT

Author(s)

AKBARY J. | ASKARI-RAD H. | EBRAHIMIZADEH M.A. | KOZEHGAR- KALEDGI A. | Issue Writer Certificate

Keywords

DIMETHYL PHTHALATEQ4

INSECT REPELLENTQ3

GELQ3

LOTIONQ4

Abstract

Background and Aim: Prior to 1940 the commonly used INSECT REPELLENT materials were substances such as citronella oil, clove oil and camphor.The outbreak of the world war 11and the need for conducting operations in many tropical areas led to an exhaustive investigation and consequently making many effective INSECT REPELLENTs. Among the best known substances was DIMETHYL PHTHALATE. The aim of this study was to synthesize of DIMETHYL PHTHALATE as a drug formulation.Method: Reaction of phthalic anhydride with absolute methanol in catalytic amount of concentrated H2S04 produced DIMETHYL PHTHALATE. This compound was formulated as a hydroalcoholic LOTION and as a GEL.Several GEL and LOTIONs with suitable stability were formulated.Results: DIMETHYL PHTHALATE was synthesizedwith 96% yield its viscosity was suitable.Conclusion: It is possible to synthesize DIMETHYL PHTHALATE from low-cost materials and formulate it to pharmaceutical preparations (e.g. LOTION or Creams), in our country.

Cites

QUANTITATIVE & QUALITATIVE DETERMINATION OF DIMETHYL PHTHALATE AND N, N'-DIETHYL-M-TOLUAMIDE IN REPELLENTS COMMERCIAL FORMULATIONS BY HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY (HPTLC)

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APA: Copy

AKBARY, J., ASKARI-RAD, H., EBRAHIMIZADEH, M.A., & KOZEHGAR- KALEDGI, A.. (2004). SYNTHESIS AND FORMULATION OF DIMETHYL PHTHALATE AS AN INSECT REPELLENT. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 6(1), 37-42. SID. https://sid.ir/paper/58915/en

Vancouver: Copy

AKBARY J., ASKARI-RAD H., EBRAHIMIZADEH M.A., KOZEHGAR- KALEDGI A.. SYNTHESIS AND FORMULATION OF DIMETHYL PHTHALATE AS AN INSECT REPELLENT. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;6(1):37-42. Available from: https://sid.ir/paper/58915/en

IEEE: Copy

J. AKBARY, H. ASKARI-RAD, M.A. EBRAHIMIZADEH, and A. KOZEHGAR- KALEDGI, “SYNTHESIS AND FORMULATION OF DIMETHYL PHTHALATE AS AN INSECT REPELLENT,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 6, no. 1, pp. 37–42, 2004, [Online]. Available: https://sid.ir/paper/58915/en

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