THE HEMODYNAMIC FFECTS OF STANDARD DOSES OF BUPIVACAINE COMPARED TO THE EFFECTS OF ITS MIXTURE WITH FENTANYL IN INTRA SPINAL ANESTHESIA AMONG AGED PEOPLE

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ZAMAN B.; AMANI F.; GHODRATI M.R.; AARABI S.A.

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Journal: JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS) Year:2004 | Volume:3 | Issue:11 Page(s): 30-36

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Title

THE HEMODYNAMIC FFECTS OF STANDARD DOSES OF BUPIVACAINE COMPARED TO THE EFFECTS OF ITS MIXTURE WITH FENTANYL IN INTRA SPINAL ANESTHESIA AMONG AGED PEOPLE

Author(s)

ZAMAN B. | AMANI F. | GHODRATI M.R. | AARABI S.A. | Issue Writer Certificate

Keywords

INTRATHECAL ANESTHESIAQ4

OPIOIDSQ3

BUPIVACAINEQ3

FENTANYLQ3

Abstract

Background & Objective: Spinal anesthesia is one of the usual techniques in the surgery of hip fractures among the aged. On the other hand, the hemodynamic complications of this method and the treatment of these complications by abundant IV liquids and drugs such as Ephedrin and phenylephedrin have potential risk for aged patients. Intrathecal OPIOIDS have synergistic effects on the duration and quality of spinal block. Thus a number of efforts have been made to prevent the hemodynamic complications and probability of inadequate block by decreasing the dosage of local anesthetic drug and adding opioid drugs to it. This study investigates the hemodynamic effects and the quality of spinal anesthesia using the above-mentioned method.Methods: Forty-six patients above 60 years of age with hip fracture were randomized into 2 groups (A and B). Group A received a spinal injection of hypertonic BUPIVACAINE (5 mg) and FENTANYL (20 g) and group B received 12.5 mg of hypertonic BUPIVACAINE for spinal anesthesia. Vital signs before and during the surgery, quality and quantity of blockage, amount of fluid and Ephedrine used were recorded every 5 minutes.Results: MAP (Mean Arterial Pressure) fell and the dosage and frequency of ephedrine consumption were significantly different in two groups. MAP decrease in-group A was 23.6 10.79 and in-group B it was 36 11.1 (p=0.001). The average requirement of ephedrine in the groups were 2.25 3.49 mg in group A and 10 8.45 mg in group B (P=0.001). The average occurrence of hypotension and ephedrine usage was 0.71 1.08 times in group A and 2.91 2.94 times in group B (p=0.001). 29 % of group A had pain in the terminal stage of surgery but this amount in group B was 13.6%. Tachycardia was 29.2 % in group A and 68.2 % in group B (p=0.001).Conclusions: Adding 20 g FENTANYL to BUPIVACAINE and decreasing its dosage can prevent the complications of INTRATHECAL ANESTHESIA. (MAP fell and the tachycardia occurred in the process of its treatment to a great extent). But to lower the incidence of failure and obtain reliable block, more controlled studies must be accomplished.

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References

COMPARISON OF MINIDOSE LIDOCAINE- FENTANYL AND CONVENTIONAL DOSE LIDOCAINE ON TRANSIENT NEUROLOGIC SYMPTOMS AFTER SPINAL ANESTHESIA

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APA: Copy

ZAMAN, B., AMANI, F., GHODRATI, M.R., & AARABI, S.A.. (2004). THE HEMODYNAMIC FFECTS OF STANDARD DOSES OF BUPIVACAINE COMPARED TO THE EFFECTS OF ITS MIXTURE WITH FENTANYL IN INTRA SPINAL ANESTHESIA AMONG AGED PEOPLE. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), 3(11), 30-36. SID. https://sid.ir/paper/59549/en

Vancouver: Copy

ZAMAN B., AMANI F., GHODRATI M.R., AARABI S.A.. THE HEMODYNAMIC FFECTS OF STANDARD DOSES OF BUPIVACAINE COMPARED TO THE EFFECTS OF ITS MIXTURE WITH FENTANYL IN INTRA SPINAL ANESTHESIA AMONG AGED PEOPLE. JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS)[Internet]. 2004;3(11):30-36. Available from: https://sid.ir/paper/59549/en

IEEE: Copy

B. ZAMAN, F. AMANI, M.R. GHODRATI, and S.A. AARABI, “THE HEMODYNAMIC FFECTS OF STANDARD DOSES OF BUPIVACAINE COMPARED TO THE EFFECTS OF ITS MIXTURE WITH FENTANYL IN INTRA SPINAL ANESTHESIA AMONG AGED PEOPLE,” JOURNAL OF ARDABIL UNIVERSITY OF MEDICAL SCIENCES (JAUMS), vol. 3, no. 11, pp. 30–36, 2004, [Online]. Available: https://sid.ir/paper/59549/en

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