PHARMACOKINETIC PARAMETER OF LITHIUM CARBONATE DRUG, MANUFACTURED IN IRAN

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MOEIN SOHEYLA; MOUSAVI M.

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Journal: Hormozgan Medical Journal Year:2002 | Volume:6 | Issue:1 Page(s): 11-14

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Information Journal Paper

Title

PHARMACOKINETIC PARAMETER OF LITHIUM CARBONATE DRUG, MANUFACTURED IN IRAN

Author(s)

MOEIN SOHEYLA | MOUSAVI M. | Issue Writer Certificate

Keywords

LITHIUMQ4

LITHIUM CARBONATEQ4

PHARMACOKINETICSQ3

Abstract

In patients with a history of mania (Bipolar patients), depression occurs simultaneously with manic attacks and the usage of LITHIUM carbonate can be effective in attack prevention. In this research the serum LITHIUM levels of 30 manic patients (using drugs produced in Iran) was examined. Treatment of manic patients or preventive therapy is based on the 12 hour LITHIUM concentration (after last usage of the drug). The results of this research showed that 12 hour-LITHIUM concentration in 40% of patients wasn't within the therapeutic range < 0.6meq/l) and this amount was within the therapeutic range in 60% patients (0.6-1.2 meq/l). there was significant statistical difference between these two amounts. In this research none of the patients were poisoned with LITHIUM. The maximum concentration after using one dosage of LITHIUM carbonate was 91% meq/l and the max time was between 1-4 hours. In comparison the Cmax and Tmax of foreign manufactured drug were reported to be between 0.6-.9 meq/l and 1-2 hours respectively.

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APA: Copy

MOEIN, SOHEYLA, & MOUSAVI, M.. (2002). PHARMACOKINETIC PARAMETER OF LITHIUM CARBONATE DRUG, MANUFACTURED IN IRAN. HORMOZGAN MEDICAL JOURNAL, 6(1), 11-14. SID. https://sid.ir/paper/60498/en

Vancouver: Copy

MOEIN SOHEYLA, MOUSAVI M.. PHARMACOKINETIC PARAMETER OF LITHIUM CARBONATE DRUG, MANUFACTURED IN IRAN. HORMOZGAN MEDICAL JOURNAL[Internet]. 2002;6(1):11-14. Available from: https://sid.ir/paper/60498/en

IEEE: Copy

SOHEYLA MOEIN, and M. MOUSAVI, “PHARMACOKINETIC PARAMETER OF LITHIUM CARBONATE DRUG, MANUFACTURED IN IRAN,” HORMOZGAN MEDICAL JOURNAL, vol. 6, no. 1, pp. 11–14, 2002, [Online]. Available: https://sid.ir/paper/60498/en

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