مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

433
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

169
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

EFFECT OF BASIC FIBROBLAST GROWTH FACTOR ON ORTHODONTIC TOOTH MOVEMENT IN RATS

Pages

  230-237

Abstract

 Objective: Basic fibroblast growth factor (bFGF) is a cytokine involved in ANGIOGENESIS, tissue remodeling and stimulation of osteoblasts and osteoclasts. The present study assesses the effects of a local injection of BFGF on the RATe of ORTHODONTIC TOOTH MOVEMENT.Materials and Methods: In this laboratory animal study, we randomly divided 50 RATs into 5 groups of 10 RATs each. RATs received 0.02 cc injections of the following doses of BFGF: group A (10ng), group B (100ng) and group C (1000ng). Group D (positive control) received an orthodontic force and injection of 0.02 cc phosphate buffered saline whereas group E (negative control) received only the anesthetic drug. A nickel titanium spring was bonded to the right maxillary first molar and incisor. After 21 days, the RATs were sacrificed and the distance between the first and second right molars was measured by a leaf gauge with 0.05 mm accuracy. ANOVA and Tukey’s HSD statistical tests were used for data analysis.Results: The greatest mean value of ORTHODONTIC TOOTH MOVEMENT was 0.7700 mm observed in group C followed by 0.6633 mm in group B, 0.5333 mm in group A, 0.2550 mm in group D and 0.0217 mm in group E. There was a significantly higher RATe of tooth movement in the test groups compared to the control groups (p<0.05). Among the test groups, the RATe of tooth movement in group C was significantly higher than group A (p<0.05). Weight changes after the intervention were not significant when compared to the baseline values, with the exception of group E (p>0.05).Conclusion: The effect of BFGF on the RATe of tooth movement was dose-dependent. Injection of 1000 ng BFGF in RATs showed the most efficacy.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    SEIFI, MASSOUD, BADIEE, MOHAMMAD REZA, ABDOLAZIMI, ZAHRA, & AMDJADI, PARISA. (2013). EFFECT OF BASIC FIBROBLAST GROWTH FACTOR ON ORTHODONTIC TOOTH MOVEMENT IN RATS. CELL JOURNAL (YAKHTEH), 15(3 (59)), 230-237. SID. https://sid.ir/paper/610390/en

    Vancouver: Copy

    SEIFI MASSOUD, BADIEE MOHAMMAD REZA, ABDOLAZIMI ZAHRA, AMDJADI PARISA. EFFECT OF BASIC FIBROBLAST GROWTH FACTOR ON ORTHODONTIC TOOTH MOVEMENT IN RATS. CELL JOURNAL (YAKHTEH)[Internet]. 2013;15(3 (59)):230-237. Available from: https://sid.ir/paper/610390/en

    IEEE: Copy

    MASSOUD SEIFI, MOHAMMAD REZA BADIEE, ZAHRA ABDOLAZIMI, and PARISA AMDJADI, “EFFECT OF BASIC FIBROBLAST GROWTH FACTOR ON ORTHODONTIC TOOTH MOVEMENT IN RATS,” CELL JOURNAL (YAKHTEH), vol. 15, no. 3 (59), pp. 230–237, 2013, [Online]. Available: https://sid.ir/paper/610390/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button