BIOLOGIC EFFECTS OF ALOE VERA EXTRACT ON BALB/C MICE EMBRYOS

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DARABI S.; TORABZADEH P.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Advances in Medical and Biomedical Research Year:2017 | Volume:24 | Issue:106 Page(s): 90-98

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Title

BIOLOGIC EFFECTS OF ALOE VERA EXTRACT ON BALB/C MICE EMBRYOS

Author(s)

DARABI S. | TORABZADEH P. | Issue Writer Certificate

Keywords

ALOE VERAQ2

PREGNANCYQ2

TERATOGENQ1

BALB / C MICEQ1

Abstract

Background and Objective: ALOE VERA plant is used in the treatment of many diseases due to its moisturizing, antimicrobial, antibacterial, antifungal, antiviral, antioxidant, and anti-inflammatory and other effects. However, owing to this plant.s various compounds, its consumption over PREGNANCY may be harmful.Materials and Methods: 2.4 g/kg of ALOE VERA extract was injected intraperitoneally to 40 mice. The first experimental group received the extract on days 3, 4, 5, 6, of PREGNANCY while the second experimental group received this extract on days 7, 8, 9, 10 of PREGNANCY. Simultaneous with these experimental groups, the control and the sham groups were considered for comparison. All mice were dissected on day 15 of PREGNANCY; fetuses were removed from uterus and the results were analyzed by one-way analysis of variance (ANOVA).Results: In the first experimental group, the weight of the placenta and fetus, Crown-Rump of fetus and placental diameter showed significant decrease (p<0.001). Likewise, in the second experimental group, there was a significant decrease in the weight of the placenta and fetus (p<0.001) and in placental diameter (p<0.001), There was no significant change in Crown-Rump of fetus compared to the control group.Moreover, abnormalities such as percutaneous bleeing, C-shaped body, syndactyly, and polyp were seen in both experimental groups.Conclusion: The results of this research elicit that ALOE VERA extract can be TERATOGEN and harmful during PREGNANCY.

Cites

THE BIOLOGICAL EFFECTS OF EPHEDRA MAJOR EXTRACT ON THE QUANTITATIVE DEVELOPMENT OF BALB/C MOUSE EMBRYOS DURING THE THIRD TO SIXTH DAYS OF PREGNANCY

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APA: Copy

DARABI, S., & TORABZADEH, P.. (2017). BIOLOGIC EFFECTS OF ALOE VERA EXTRACT ON BALB/C MICE EMBRYOS. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 24(106), 90-98. SID. https://sid.ir/paper/61080/en

Vancouver: Copy

DARABI S., TORABZADEH P.. BIOLOGIC EFFECTS OF ALOE VERA EXTRACT ON BALB/C MICE EMBRYOS. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2017;24(106):90-98. Available from: https://sid.ir/paper/61080/en

IEEE: Copy

S. DARABI, and P. TORABZADEH, “BIOLOGIC EFFECTS OF ALOE VERA EXTRACT ON BALB/C MICE EMBRYOS,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 24, no. 106, pp. 90–98, 2017, [Online]. Available: https://sid.ir/paper/61080/en

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