EFFECT OF GONADECTOMY ON GENDER DIFFERENCES OF THERMAL PAIN SENSE THRESHOLD IN RAT

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SHAMSI MEYMANDI M.

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Journal: Journal of Kerman University of Medical Sciences Year:2001 | Volume:8 | Issue:4 Page(s): 226-231

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Information Journal Paper

Title

EFFECT OF GONADECTOMY ON GENDER DIFFERENCES OF THERMAL PAIN SENSE THRESHOLD IN RAT

Author(s)

SHAMSI MEYMANDI M. | Issue Writer Certificate

Keywords

GONADECTOMYQ4

THERMALPAIN THRESHOLDQ4

REACTIONTIMEQ3

RATQ2

Abstract

The previous studies have been suggested that tolerance, sensitivity and pain threshold are different between men and women. These differences can be affected by various factors. In this study, the effect of GONADECTOMY on gender differences in thermal pain threshold was tested by hot plate method in RATs. 0Therefore the reaction time (the delay occurred in response to thermal stimulus) at zero, 15 and 30 minutes was redistricted. Mean of those 3 values was respected as thermal pain sense threshold. Then the gonads were occluded and the pain sense threshold at 7th, 21st and 35th days was measured. The results were compared between sexes and also in each sex in different days. The results showed no gender differences before GONADECTOMY. However after GONADECTOMY the thermal pain threshold was decreased in both sexes and reached to its minimum value on 21st day and returned to basal value on day 35 in both sexes. Although this reduction was more dominant in males, no significant difference was observed between sexes. GONADECTOMY in males caused a significant reduction of pain threshold in 7th and 21st days; GONADECTOMY in females had no effect. In conclusion it seems that female sex hormones have no effect on thermal pain threshold, but testosterone was effective. Since pain sense threshold was also returned to basal value in male RATs, we concluded that stimulatory effect of testosterone (up to day 21) may be more important than their organizational effects that appear after 30th day.

Cites

COMPARISON OF THE EFFECTS OF PROGESTERONE, ALLOPREGNANOLONE AND GENDER ON SUPRESSING EDEMA FORMATION AFTER TRAUMATIC BRAIN INJURY IN RATS

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APA: Copy

SHAMSI MEYMANDI, M.. (2001). EFFECT OF GONADECTOMY ON GENDER DIFFERENCES OF THERMAL PAIN SENSE THRESHOLD IN RAT. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 8(4), 226-231. SID. https://sid.ir/paper/611/en

Vancouver: Copy

SHAMSI MEYMANDI M.. EFFECT OF GONADECTOMY ON GENDER DIFFERENCES OF THERMAL PAIN SENSE THRESHOLD IN RAT. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2001;8(4):226-231. Available from: https://sid.ir/paper/611/en

IEEE: Copy

M. SHAMSI MEYMANDI, “EFFECT OF GONADECTOMY ON GENDER DIFFERENCES OF THERMAL PAIN SENSE THRESHOLD IN RAT,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 4, pp. 226–231, 2001, [Online]. Available: https://sid.ir/paper/611/en

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