Screening Efficacy of Available HIV Protease Inhibitors on COVID-19 Protease

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MIRZAEI MAHMOUD; Harismah kun; DaI Muhammad; Salarrezaei Elham; ROSHANDEL ZAHRA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MILITARY MEDICINE Year:2020 | Volume:22 | Issue:2 Page(s): 100-107

Download Full-Text

Persian Verion

View:

813

Download:

Cites:

Information Journal Paper

Title

Screening Efficacy of Available HIV Protease Inhibitors on COVID-19 Protease

Author(s)

Keywords

COVID-19Q1

ScreeningQ1

ProteaseQ1

HIVQ1

Abstract

Background and Aim: Advent of COVID-19 attracted the attentions of researchers to develop drugs for its treatment. Besides efforts on developing new drugs, Screening available drugs to see their efficacy on COVID-19 could be an urgent action of initiating its pharmacotherapy. In this study, efficacy of HIV Protease inhibitors on COVID-19 Protease has been examined. Methods: Molecular docking based Screening by AutoDock software has been done to examine the efficacy of ligand-receptor interactions. Results: Obtained results of binding energy, inhibitory constant and interactions quality have approved the idea of efficacy of HIV Protease inhibitors on COVID-19 Protease. Conclusion: Quantitative results indicated different levels of efficacy of investigated ligands for inhibitory activity of COVID-19 and qualitative results indicated various localizations of ligands in the proposed active site of Protease. The concluding remarks of this study are to introduce Nelfinavir as the best ligand in quantitative respect and each of Saquinavir, Amprenavir and Fosamprenavir as the best ligands inqualitative respect for possible inhibitory effects on COVID-19 Protease.

Cites

No record.

References

No record.

Cite

APA: Copy

MIRZAEI, MAHMOUD, Harismah, kun, DaI, Muhammad, Salarrezaei, Elham, & ROSHANDEL, ZAHRA. (2020). Screening Efficacy of Available HIV Protease Inhibitors on COVID-19 Protease. JOURNAL OF MILITARY MEDICINE, 22(2 ), 100-107. SID. https://sid.ir/paper/61825/en

Vancouver: Copy

MIRZAEI MAHMOUD, Harismah kun, DaI Muhammad, Salarrezaei Elham, ROSHANDEL ZAHRA. Screening Efficacy of Available HIV Protease Inhibitors on COVID-19 Protease. JOURNAL OF MILITARY MEDICINE[Internet]. 2020;22(2 ):100-107. Available from: https://sid.ir/paper/61825/en

IEEE: Copy

MAHMOUD MIRZAEI, kun Harismah, Muhammad DaI, Elham Salarrezaei, and ZAHRA ROSHANDEL, “Screening Efficacy of Available HIV Protease Inhibitors on COVID-19 Protease,” JOURNAL OF MILITARY MEDICINE, vol. 22, no. 2 , pp. 100–107, 2020, [Online]. Available: https://sid.ir/paper/61825/en

Related Journal Papers