COMRARISON OF THE SENSORY AND MOTOR BLOCK DURATION OF INTRATHECAL LIDOCAINE 5%, LIDOCAINE 5% PLUS EPINEPHRINE AND LIDOCAINE 5% PLUS DEXAMETHASONE

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MOAFEGH A.; GHAFFARI M.H.; EGHTESADI ARAGHI P.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2003 | Volume:24 | Issue:43 Page(s): 57-65

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Title

COMRARISON OF THE SENSORY AND MOTOR BLOCK DURATION OF INTRATHECAL LIDOCAINE 5%, LIDOCAINE 5% PLUS EPINEPHRINE AND LIDOCAINE 5% PLUS DEXAMETHASONE

Author(s)

MOAFEGH A. | GHAFFARI M.H. | EGHTESADI ARAGHI P. | Issue Writer Certificate

Keywords

INTRATHECAL DEXAMETHASONEQ4

LIDOCAINEQ3

SPINAL ANESTHESIAQ3

DURATION OF SENSORY BLOCKQ4

DURATION OF MOTOR BLOCKQ4

Abstract

The action of corticosteroids in prolongation of the analgesic effects of local anesthetics in peripheral nerves is well documented. The objective of this study is to compare the sensory and motor blockade duration of intrathecal LIDOCAINE plus dexamthasone versus plain LIDOCAINE and LIDOCAINE plus epinephrine.Ninety ASA I or II 20 to 45 year old men, undergoing lower abdominal surgery under SPINAL ANESTHESIA with less than 60 min duration and sensory level lower than T6, in Dr. Shariaty Hospital in winter 1381, were selected for the randomized double blind prospective study. The patients were randomly allocated to LIDOCAINE- dexamethasone (75mg LIDOCAINE plus 8mg dexamethasone intrathecally), LIDOCAINE (75mg LIDOCAINE plus 2ml normal saline intrathecally) and LIDOCAINE- epinephrine (75mg LIDOCAINE plus 0.2mg epinephrine 1/1000 and 2 ml normal saline intrathecally) groups. Four level regression of sensory level was assumed as the end of sensory block. The duration of sensory and motor block, hypotension, bradycardia, nausea and vomiting and neurological complications were assessed.There was no significant difference between age, weight, ASA class initiation time of sensory and motor block and time in attaining the highest level of block. The DURATION OF SENSORY BLOCK was significantly longer in the LIDOCAINE - epinephrine and LIDOCAINE- dexamethasone groups than the LIDOCAINE group (respectively 85.7 and 82.1 min vs. 55.9 min for sensory block and 112.8 and 118.9 min vs. 79.2 for motor block; p<0.001). The incidence of nausea and vomiting and antiemetic administration, hypotension and bradycardia that needed treatment had no significant difference (p>0.05). No neurological deficit or other significant adverse effects were recorded.The addition of intrathecal dexamthasone to LIDOCAINE significantly improves the duration of sensory and motor block following spinal anaesthesia without significant side-effects.

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APA: Copy

MOAFEGH, A., GHAFFARI, M.H., & EGHTESADI ARAGHI, P.. (2003). COMRARISON OF THE SENSORY AND MOTOR BLOCK DURATION OF INTRATHECAL LIDOCAINE 5%, LIDOCAINE 5% PLUS EPINEPHRINE AND LIDOCAINE 5% PLUS DEXAMETHASONE. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 24(43), 57-65. SID. https://sid.ir/paper/63379/en

Vancouver: Copy

MOAFEGH A., GHAFFARI M.H., EGHTESADI ARAGHI P.. COMRARISON OF THE SENSORY AND MOTOR BLOCK DURATION OF INTRATHECAL LIDOCAINE 5%, LIDOCAINE 5% PLUS EPINEPHRINE AND LIDOCAINE 5% PLUS DEXAMETHASONE. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2003;24(43):57-65. Available from: https://sid.ir/paper/63379/en

IEEE: Copy

A. MOAFEGH, M.H. GHAFFARI, and P. EGHTESADI ARAGHI, “COMRARISON OF THE SENSORY AND MOTOR BLOCK DURATION OF INTRATHECAL LIDOCAINE 5%, LIDOCAINE 5% PLUS EPINEPHRINE AND LIDOCAINE 5% PLUS DEXAMETHASONE,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 24, no. 43, pp. 57–65, 2003, [Online]. Available: https://sid.ir/paper/63379/en

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