EFFICACY ASSESSMENT OF INTRAVENOUS DEXAMETHASONE IN PREVALENCE AND SEVERITY OF POSTOPERATIVE PAIN: A CLINICAL TRIAL

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RAHIMI M.; FOLADFAR F.

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Paper Information

Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2005 | Volume:27 | Issue:49 Page(s): 35-42

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Title

EFFICACY ASSESSMENT OF INTRAVENOUS DEXAMETHASONE IN PREVALENCE AND SEVERITY OF POSTOPERATIVE PAIN: A CLINICAL TRIAL

Author(s)

RAHIMI M. | FOLADFAR F. | Issue Writer Certificate

Keywords

POSTOPERATIVE PAINQ3

INCIDENCEQ3

INTENSITYQ2

DEXAMETHASOREQ3

Abstract

Background and Objective: POSTOPERATIVE PAIN accounts one of the most disturbing complications after various surgeries and could result in harmful physiologic consequence. Some investigators had reported that corticosteroids effectively induce and prolong the duration of local anesthetics. The aim of this study was to assess the efficacy of intravenous dexamethasone in prevalence and severity of POSTOPERATIVE PAIN. Materials and Method: In a randomized, double-blinded, placebo- controlled prospective study, 30 ASA I & 11, male above and under 50 years-old patients scheduled for elective surgical reconstruction of inguinal hernia under general anesthesia were enrolled and randomly assigned into control or case groups. Before induction of anesthesia, in control group, normal saline (2 ml) and in case group, dexamethasone (8 mg, 2 ml) was injected intravenously. The time between the ends of the surgery and pain beginning, occurrence and severity of POSTOPERATIVE PAIN by Visual Analoue scale (VAS) and the total postoperative administered analgesic dose were measured. Results: The age mean was 38.37±18.80. There were no significant defenses in means of age, surgery duration and fentanyl administration during surgery between control and case groups. The mean of pain severity (VAS) and the overall administered analgesic dose were significantly lower and time between surgery completion and pain initiation was significantly longer in case group compared to control group (p<0.05, Mann- Whitney Test). There were no significant differences between mentioned variables (except age) in above and under 50 years-old groups. In case group pain severity (VAS) was significantly higher over 50 years-old compared to under 50 years-old and the time between end of surgery and pain beginning was significantly longer (p<0.05, Mann-Whitney Test). Conclusion: Intravenous administration of 8 mg intravenous dexamethasone before induction of anesthesia significantly decreases the POSTOPERATIVE PAIN severity and the total administered analgesic and increases time betweeen the end of the surgery and pain beginning.

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APA: Copy

RAHIMI, M., & FOLADFAR, F.. (2005). EFFICACY ASSESSMENT OF INTRAVENOUS DEXAMETHASONE IN PREVALENCE AND SEVERITY OF POSTOPERATIVE PAIN: A CLINICAL TRIAL. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 27(49), 35-42. SID. https://sid.ir/paper/63422/en

Vancouver: Copy

RAHIMI M., FOLADFAR F.. EFFICACY ASSESSMENT OF INTRAVENOUS DEXAMETHASONE IN PREVALENCE AND SEVERITY OF POSTOPERATIVE PAIN: A CLINICAL TRIAL. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2005;27(49):35-42. Available from: https://sid.ir/paper/63422/en

IEEE: Copy

M. RAHIMI, and F. FOLADFAR, “EFFICACY ASSESSMENT OF INTRAVENOUS DEXAMETHASONE IN PREVALENCE AND SEVERITY OF POSTOPERATIVE PAIN: A CLINICAL TRIAL,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 27, no. 49, pp. 35–42, 2005, [Online]. Available: https://sid.ir/paper/63422/en

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